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https://www.sciencedirect.com/science/article/pii/B9780128179093000169
The general desired characteristics of the polymer in a mucoadhesive protein or peptide delivery system include proper hydrophilicity of the polymer to interact properly with the high amounts of water present in the mucus layer, a high molecular weight to increase the possibility of interactions, and proper surface tension to allow spreading of the polymer onto the mucosal layer.Author: Pran Kishore Deb, Omar Al-Attraqchi, Balakumar Chandrasekaran, Anant Paradkar, Rakesh K. Tekade
https://www.sciencedirect.com/science/article/pii/B978008100736500017X
Antimicrobial peptide-based drug delivery systems Peptides with antimicrobial properties, named antimicrobial peptides (AMPs), behave as well as efficient delivery vectors of bioactive substances, including drugs, in many applications, such as cancer, genetic disorders, cardiovascular, infectious, and inflamatory diseases.Author: Dana M. Copolovici, Andreea I. Lupitu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792531/
Designing oral peptide and protein delivery systems has been a persistent challenge to pharmaceutical scientists because of their several unfavorable physicochemical properties including large molecular size, susceptibility to enzymatic degradation, short plasma half-life, ion permeability, immunogenicity, and the tendency to undergo aggregation, adsorption, and denaturation 12,13. Consequently, the absolute …
http://rjptonline.org/AbstractView.aspx?PID=2019-12-3-69
Peptides and proteins are complex architecture therapeutics useful in several diseases. Several pharmaceutical and biopharmaceutical challenges limit their clinical applications. Continuous efforts are focussed for formulation of this therapeutics into safe and effective delivery systems.Author: L. Srinivas, V. Manikanta, M. Jaswitha
https://www.ijpsonline.com/articles/protein-and-peptide-drug-delivery-oral-approaches.html
Nov 10, 2006 · A primary objective of oral delivery systems is to protect protein and peptide drugs from acid and luminal proteases in the GIT. To overcome these barriers, several formulation strategies are being investigated.Author: Jessy Shaji, V Patole
https://www.slideshare.net/BrajeshKumar67/protein-and-peptide-drug
May 24, 2015 · Contents I. Protein & Peptides II. Structure of protein III. Classification of protein IV. Drug delivery system V. Stability testing VI. Conclusion VII. Protein & Peptides PROTEINS: Proteins are the large organic compounds made of amino acids arranged in a linear chain and joined together by peptide bonds. Continue….
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