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https://www.slideshare.net/BrajeshKumar67/protein-and-peptide-drug
May 24, 2015 · protein and peptide drug delivery system 1. PROTEIN AND PEPTIDE DRUG DELIVERY SYSTEM PRESENTED BY BRAJESH KUMAR M. PHARM (1ST YEAR) PHARMACEUTICS BBAU LUCKNOW , 1 2. Contents I. Protein & Peptides II. Structure of protein III. Classification of protein IV. Drug delivery system V. Stability testing VI. Conclusion VII. References 2 3.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956587/
Barriers to oral delivery. Oral delivery is the preferred route of drug administration, as the majority of patients see it as the most convenient way to take their drugs [].Drugs taken by the oral route have the highest level of patient compliance due to the ease and simplicity of taking medications [11,12].Despite the large number of protein therapeutics being discovered each year, oral ...Author: Benjamin J Bruno, Geoffrey D Miller, Carol S Lim
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792531/
Designing and formulating a protein and peptide drug for delivery though GI tract requires a multitude of strategies. The dosage form must initially stabilize the drug making it easy to take orally 4. It must then protect the drug from the extreme acidity and action of pepsin in the stomach.
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/protein-drug-delivery
Formulation of protein and peptide drugs, their route of administration, rate, and overall pharmacokinetic profile in the body are pivotal factors in deciding the success of protein drug delivery. Until the 1950s, the oral route of drug delivery was the most preferred, along with transport by single-cell epithelial barriers.
https://www.sciencedirect.com/science/article/pii/S0169409X14002117
Protein inhalation is a delivery route which offers high potential for direct local lung application of proteins. Liquid formulations are usually available in early stages of biopharmaceutical development and nebulizers are the device of choice for atomization avoiding additional process steps like drying and enabling fast progression to clinical trials.Author: Sebastian P. Hertel, Gerhard Winter, Wolfgang Friess
https://link.springer.com/content/pdf/10.1208%2Fs12249-019-1325-z.pdf
protein polypeptide drug. BARRIERS TO ORAL DELIVERY OF PROTEIN AND PEPTIDE DRUG NPS Most of the protein and peptide drugs are macromolec-ular hydrophilic, in the extreme environment of gastrointes-tinal stability, susceptible to gastric acid and pepsin degradation; at the same time, because of its hydrophilicity,Author: Shu-jun Cao, Shuo Xu, Hui-ming Wang, Yong Ling, Jiahua Dong, Rui-dong Xia, Xiang-hong Sun
https://www.researchgate.net/publication/328265448_PROTEIN_AND_PEPTIDE_DRUG_DELIVERY_SYSTEM
Protein and Peptide drug delivery system are the Novel drug Delivery System. Proteins and peptides are the most abundant components of biological cells. They exist functioning such as enzymes ...
http://www.pharmtech.com/considering-protein-and-peptide-delivery
Jan 02, 2019 · Drug delivery challenges posed by protein and peptide therapeutics are many. Not only are the molecules large in size but they are hydrophilic, cannot easily cross biological barriers, are degraded by enzymes, rapidly leave the circulation system, and are highly charged, all of which complicate the delivery strategy.
http://rjptonline.org/HTMLPaper.aspx?Journal=Research%20Journal%20of%20Pharmacy%20and%20Technology;PID=2019-12-3-69
Protein drug delivery through emulsions and microemulsions is one of the promising approach in biomedical, pharmaceutical, and cosmetics. Delivery of influenza vaccine and diphtheria toxoid, BSA in emulsions is the proven examples. They offer wide range in applications such as protection, ...Author: L. Srinivas, V. Manikanta, M. Jaswitha
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