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https://www.sciencedirect.com/science/article/pii/B9780128179093000169
Various protein/peptide drug delivery systems have been extensively investigated to overcome the problems associated with the exogenous administration of protein and peptide therapeutics. In this chapter, different approaches for the delivery of proteins and peptides are discussed including chemical modifications, absorption enhancers, carrier systems, and various other approaches.Author: Pran Kishore Deb, Omar Al-Attraqchi, Balakumar Chandrasekaran, Anant Paradkar, Rakesh K. Tekade
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792531/
Designing oral peptide and protein delivery systems has been a persistent challenge to pharmaceutical scientists because of their several unfavorable physicochemical properties including large molecular size, susceptibility to enzymatic degradation, short plasma half-life, ion permeability, immunogenicity, and the tendency to undergo ...
http://rjptonline.org/AbstractView.aspx?PID=2019-12-3-69
Peptides and proteins are complex architecture therapeutics useful in several diseases. Several pharmaceutical and biopharmaceutical challenges limit their clinical applications. Continuous efforts are focussed for formulation of this therapeutics into safe and effective delivery systems.Author: L. Srinivas, V. Manikanta, M. Jaswitha
http://www.authorstream.com/Presentation/pharmawick-1969759-protein-peptide-drug-delivery/
Oct 24, 2013 · 8 Advantages of protein and peptide drug delivery system Erythropoietin used for production of RBC. Tissue plasminogen activator is used for Heart attack, Stroke. Oxytocin maintain labor pain. Bradykinin increases the peripheral circulation. Somatostatin decrease bleeding in gastric ulcer. Gonadotropin induce ovulation.
https://www.researchgate.net/publication/319122467_An_over_view_Protein_and_peptide_based_drug_delivery
In the last three decades therapeutic peptides and proteins have risen in prominence as potential drug of future. Proteins are polymers consisting of amino acids covalently linked by peptide bonds. Peptides are small proteins composed of up to a few dozen amino acids proteins are rapidly degraded by digestive enzymes.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956587/
As a whole, protein and peptide drugs have low bioavailability when administered orally due to problematic barriers including gastrointestinal proteases, the epithelial barrier and efflux pumps. Common routes of administration for the systemic delivery of peptide and protein therapeutics are …Author: Benjamin J Bruno, Geoffrey D Miller, Carol S Lim
https://innovareacademics.in/journal/ijcpr/Issues/Vol3Issue2/286.pdf
these therapeutic proteins and peptides are made available, it will be essential to formulate these drugs into safe and effective delivery systems. Due to its wider applications in pharmaceutical industries, they will replace many existing organic based pharmaceuticals. Now days, many drugs
https://www.slideshare.net/ManoharKengar/protein-peptide-drug-delivery-system-barrier
Nov 16, 2017 · Protein > 50 amino acids Peptides: These are short polymers formed from the linking, in a defined order of amino acids. peptide < 50 amino acids 16/11/2017 3 4. The protein and peptides are very important in biological cells. Lack of proteins and peptides causes diseases like Diabetes mellitus.
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