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https://www.pharmaceutical-journal.com/drug-delivery-progress-and-problems/20003039.article
Drug delivery: progress and problems. Four half-day sessions at the Conference were devoted to discussion on aspects of drug delivery. The sessions were organised in association with the UKI Controlled Release Society The biochemical barriers that can hinder effective drug delivery, and possible ways of overcoming them, were discussed by ...
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Drugs have long been used to improve health and extend lives. The practice of drug delivery has changed dramatically in the past few decades and even greater changes are …
http://www.americanpharmaceuticalreview.com/Featured-Articles/345540-Opportunities-and-Challenges-in-Biologic-Drug-Delivery/
Dec 22, 2017 · New, more advanced drug delivery technology can circumvent many of these problems if incorporated at early stages of drug development to create combination products that can impact outcomes positively. Biologics, when combined with these patient-centric delivery devices, hold promise of improved outcomes, lower cost and greater commercial success.
https://www.ncbi.nlm.nih.gov/books/NBK200818/
Noting that the most difficult part of a drug discovery effort often involves solving a drug delivery problem, Morones-Ramírez concluded his talk with a description of the antibiotic delivery system his group is developing using biocompatible microbial exopolymers.Author: Division on Earth
http://www.pharmtech.com/four-challenges-pulmonary-drug-delivery
Sep 01, 2017 · Pulmonary drug delivery is becoming increasingly used. When developing pulmonary drugs, pharmaceutical chemists must consider drug absorption, control of particle size, suitable toxicology models, and patient compliance. The author reviews the issues specific to developing drugs designed for pulmonary delivery and considers how—with the right knowledge and expertise—these challenges …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627459/
Aug 15, 2015 · In contrast to targeted drug delivery systems, local drug delivery systems are typically administered to the sites of action directly. Most local drug delivery systems are for local therapeutic effects with only a few exceptions, such as transdermal nitroglycerin whose indication is the prevention of angina pectoris due to coronary artery disease.Author: Hong Wen, Huijeong Jung, Xuhong Li
https://www.sciencedirect.com/science/article/pii/S0032386108000487
This limitation may not be important in many typical drug delivery applications (e.g. subcutaneous injection). More important, perhaps, are problems relating to the drug delivery properties of hydrogels. The quantity and homogeneity of drug loading into hydrogels may be limited, particularly in the case of hydrophobic drugs.Author: Todd R. Hoare, Daniel S. Kohane
https://lowninstitute.org/off-label-on-demand-the-problems-with-drug-delivery-start-ups/
Apr 10, 2019 · Off-label, on-demand: The problems with drug delivery start-ups By Judith Garber April 10, 2019 You may have seen the advertisements for companies like Hims, Kick, and Roman, that promise an easier way to access prescription drugs for conditions such …
https://www.sciencedirect.com/science/article/pii/S1474667017615180
In terms of the control drug delivery itself, there are still some problems to be resoved relating to the actual delivery system, such as in mai~ taining a constant rate of infusion of drugs such as sodium nitro-prusside OL digoxin.Author: Claudio Cobelli, Ewart Carson, Howard J. Chizeck, Donald M. Wiberg
https://www.medscape.com/viewarticle/770397_5
Nov 01, 2019 · Nanotechnology has the potential to revolutionize drug delivery, but challenges remain. This article summarizes recent developments in the use of nanoparticles as drug delivery systems.
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