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https://www.sciencedirect.com/science/article/pii/S0928098706001497
From a formulation perspective proteins are complex and therefore challenging molecules to develop drug delivery systems for. The success of a formulation depends on the ability of the protein to maintain the native structure and activity during preparation and delivery as well as during shipping and long-term storage of the formulation.Author: L. Jorgensen, E.H. Moeller, M. van de Weert, H.M. Nielsen, S. Frokjaer
https://www.researchgate.net/publication/6957637_Preparing_and_evaluating_delivery_systems_for_proteins
Preparing and evaluating delivery systems for proteins Article · Literature Review in European Journal of Pharmaceutical Sciences 29(3-4):174-82 · December 2006 with 21 Reads How we measure 'reads'
https://research.ku.dk/search/?pure=en%2Fpublications%2Fpreparing-and-evaluating-delivery-systems-for-proteins(3a8e0f3e-6b95-438b-a900-5720adfc83cf).html
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655889/
Apr 27, 2013 · One of the most challenging problems in the development of protein pharmaceuticals is to deal with stabilities of proteins due to its complicated structures. ... Proteins play crucial roles in virtual pharmaceutical science ... Jorgensenl L, Moeller EH, Weert V, Nielsen HM, Frokjaer S. Preparing and evaluating delivery systems for proteins. Eur ...Author: Fei Wu, Zhihua Zhou, Jing Su, Liangming Wei, Weien Yuan, Tuo Jin
https://www.sciencedirect.com/journal/european-journal-of-pharmaceutical-sciences/vol/29/issue/3
select article Preparing and evaluating delivery systems for proteins. ... Review article Full text access Preparing and evaluating delivery systems for proteins. L. Jorgensen, E.H. Moeller, M. van de Weert, H.M. Nielsen, S. Frokjaer. Pages 174-182 Download PDF. Article preview. Research paper.
https://link.springer.com/article/10.1208/s12249-008-9148-3
Dec 16, 2008 · Abstract. While the concept of using polymer-based sustained-release delivery systems to maintain therapeutic concentration of protein drugs for extended periods of time has been well accepted for decades, there has not been a single product in this category successfully commercialized to date despite clinical and market demands.Author: Fei Wu, Tuo Jin
https://pubs.acs.org/doi/abs/10.1021/bi00345a005
Mechanism of polyethylene glycol interaction with proteins. Tsutomu Arakawa; Serge N. Timasheff; Cite this: ... Preparing and evaluating delivery systems for proteins. European Journal of Pharmaceutical Sciences 2006, 29 ... Factors affecting short-term and long-term stabilities of proteins. Advanced Drug Delivery Reviews 2001, 46 (1-3) , 307 ...Author: Tsutomu Arakawa, Serge N. Timasheff
https://link.springer.com/article/10.1186/1556-276X-8-197
Apr 27, 2013 · One of the most challenging problems in the development of protein pharmaceuticals is to deal with stabilities of proteins due to its complicated structures. This study aims to develop a novel approach to stabilize and encapsulate proteins into dextran nanoparticles without contacting the interface between the aqueous phase and the organic phase.Author: Fei Wu, Zhihua Zhou, Jing Su, Liangming Wei, Weien Yuan, Tuo Jin
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471357/
Mar 15, 2019 · Co-delivery systems ideally possess the potential for encapsulation of both hydrophobic and hydrophilic drugs. Platforms for co-delivery systems should be designed to carry both traditional chemotherapeutics and cell regulatory molecules, such as nucleic acids . Although much progress has been made with nanotechnology-based co-delivery systems ...Author: Jiayi Pan, Kobra Rostamizadeh, Nina Filipczak, Vladimir P. Torchilin
https://www.nature.com/articles/nnano.2007.149
Jun 10, 2007 · a, Evaluating the delivery of 200-nm particles into KB cells (red line) by flow cytometry. Treated cells were stained with phycoerythrin (PE)-labelled anti-mouse IgG antibodies before (blue line ...Author: Demir Akin, Jennifer Sturgis, Kathy Ragheb, Debby Sherman, Kristin Burkholder, J. Paul. Robinson, Ar...
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