We have collected information about Preclinical Models For Pulmonary Drug Delivery for you. Follow the links to find out details on Preclinical Models For Pulmonary Drug Delivery.
https://www.researchgate.net/publication/339275335_Innovative_preclinical_models_for_pulmonary_drug_delivery_research
Introduction: Pulmonary drug delivery is a complex field of research combining physics which drive aerosol transport and deposition and biology which underpins efficacy and toxicity of inhaled drugs.
https://www.ncbi.nlm.nih.gov/pubmed/32057260
Feb 23, 2020 · Innovative preclinical models for pulmonary drug delivery research. ... Introduction: Pulmonary drug delivery is a complex field of research combining physics which drive aerosol transport and deposition and biology which underpins efficacy and toxicity of inhaled drugs. A myriad of preclinical methods, ranging from in-silico to in-vitro, ex ...Author: Stephan Ehrmann, Stephan Ehrmann, Otmar Schmid, Chantal Darquenne, Barbara Rothen-Rutishauser, Josue...
https://www.researchgate.net/publication/38032158_Preclinical_models_for_pulmonary_drug_delivery
This review describes relevant drug delivery models for preclinical evaluation of inhaled drug products. Epithelial cell culture models, the isolated perfused lung and in vivo models are reviewed.
https://www.sciencedirect.com/science/article/pii/S0169409X14002191
This review focuses on models to assess safety and efficacy in the preclinical stage in the context of inhaled antimicrobials and drug delivery systems. 2. Preclinical models currently used in pulmonary drug delivery 2.1. Barriers to pulmonary drug delivery. Pulmonary drug delivery offers a great opportunity to administer drugs in a non ...Author: Marius Hittinger, Jenny Juntke, Stephanie Kletting, Nicole Schneider-Daum, Cristiane de Souza Carval...
https://www.tandfonline.com/doi/figure/10.1080/17425247.2020.1730807
Introduction: Pulmonary drug delivery is a complex field of research combining physics which drive aerosol transport and deposition and biology which underpins efficacy and toxicity of inhaled drugs.A myriad of preclinical methods, ranging from in-silico to in-vitro, ex–vivo and in-vivo, can be implemented.. Areas covered: The present review covers in-silico mathematical and computational ...
https://www.tandfonline.com/doi/abs/10.1517/17425240903241788
Apr 19, 2012 · Over the last years, several models have been developed in order to study the efficacy and safety of pulmonary drug delivery. Objective: This review describes relevant drug delivery models for preclinical evaluation of inhaled drug products. Methods: Epithelial cell culture models, the isolated perfused lung and in vivo models are reviewed. The ...Author: Cláudia A. Fernandes, Rita Vanbever
http://www.pharmtech.com/four-challenges-pulmonary-drug-delivery
Sep 01, 2017 · Pulmonary drug delivery is becoming increasingly used. When developing pulmonary drugs, pharmaceutical chemists must consider drug absorption, control of particle size, suitable toxicology models, and patient compliance. The author reviews the issues specific to developing drugs designed for pulmonary delivery and considers how—with the right knowledge and expertise—these challenges …
https://www.sciencedirect.com/science/article/pii/B9780128157206000101
Pulmonary delivery has been proved to be therapeutically more effective than i.v. injection for various nanocarriers in many in vivo preclinical models , , , . When aerosolized, drug-loaded nanocarriers have also led to improved antitumor efficacy compared to free drug in solution [61] .Author: Rémi Rosiere, Karim Amighi, Nathalie Wauthoz
https://dial.uclouvain.be/pr/boreal/object/boreal:28495
Over the last years, several models have been developed in order to study the efficacy and safety of pulmonary drug delivery. OBJECTIVE: This review describes relevant drug delivery models for preclinical evaluation of inhaled drug products. METHODS: Epithelial cell culture models, the isolated perfused lung and in vivo models are reviewed.Author: Cláudia A. Fernandes, Rita Vanbever
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6161314/
Despite the interest in evaluating particulate-based vaccines for pulmonary delivery, successful translation of drug and vaccine candidates from the preclinical to the clinical trial stage has been abysmal. One of the reasons for the poor clinical translation is the lack of effective pulmonary delivery tools for preclinical studies.Author: Nitesh K. Kunda, Dominique N. Price, Pavan Muttil
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