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https://www.ncbi.nlm.nih.gov/pubmed/22954323
Self-nanoemulsifying drug delivery systems (SNEDDS) have emerged as a vital strategy to formulate these poorly soluble compounds for bioavailability enhancement. AREAS COVERED: The review gives an insight about potential of SNEDDS with regards to oral drug delivery.Author: Abdul Wadood Khan, Sabna Kotta, Shahid H Ansari, Rakesh Kumar Sharma, Javed Ali
https://www.researchgate.net/publication/230809790_Potentials_and_challenges_in_self-nanoemulsifying_drug_delivery_systems
Self-nanoemulsifying drug delivery systems (SNEDDS) are a vital strategy that combines benefits of LBDDS and nanotechnology. SNEDDS are now preferred to improve the formulation of drugs with poor ...
https://www.tandfonline.com/doi/full/10.1517/17425247.2012.719870
Mar 27, 2014 · Self-nanoemulsifying drug delivery systems (SNEDDS) have emerged as a vital strategy to formulate these poorly soluble compounds for bioavailability enhancement. Areas covered: The review gives an insight about potential of SNEDDS with regards to oral drug delivery. The effect of various key constituents on formulation of SNEDDS and their ...Author: Abdul Wadood Khan, Sabna Kotta, Shahid H Ansari, Rakesh Kumar Sharma, Javed Ali
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6572212/
May 24, 2019 · Background and Objectives: Lipid-based self-nanoemulsifying drug delivery systems (SNEDDS) have resurged the eminence of nanoemulsions by modest adjustments and offer many valuable opportunities in drug delivery. Chlorpromazine, an antipsychotic agent with poor aqueous solubility—with extensive first-pass metabolism—can be a suitable candidate for the development of …Author: Jeand Baloch, Muhammad Farhan Sohail, Hafiz Shaib Sarwar, Maria Hassan Kiani, Gul Majid Khan, Sarwat...
https://www.sciencedirect.com/science/article/pii/B9780128136898000021
Nanoparticle drug delivery systems (NPDDS) achieve superior entry for the particles inside the body, as their size permits conveyance by means of intravenous infusion or different courses. Another important use of the NPDDS is in the production of the antibodies based specific proteins …Author: Deepti Sharma, Navneet Sharma, Mallika Pathak, Paban K. Agrawala, Mitra Basu, Himanshu Ojha
https://www.mdpi.com/1420-3049/25/7/1703/htm
Background: Bioactive oils of natural origin have gained huge interests from health care professionals and patients. Objective: To design a bioactive self-nanoemulsifying drug delivery system (Bio-SNEDDS) comprising curcumin (CUR) and piperine (PP) by incorporating bioactive natural oils in the formulation. Methods: The self-emulsifying properties of apricot, avocado, black seed and ...
https://www.tandfonline.com/doi/pdf/10.3109/10717544.2014.896058
Self-microemulsifying drug delivery system (SMEDDS) has emerged as a vital strategy to formulate poor water soluble compounds for bioavailability enhancement. However, certain limitations are associated with SMEDDS formulations which include in vivo drug precipitation,
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217686/
Irbesartan (IRB) is an angiotensin II receptor blocker antihypertensive agent. The aim of the present investigation was to develop a self-nanoemulsifying drug delivery system (SNEDDS) to enhance the oral bioavailability of poorly water-soluble IRB. The solubility of IRB in various oils was determined to identify the oil phase of SNEDDS.
https://www.sciencedirect.com/science/article/pii/S1549963420300538
Apr 07, 2020 · Carvedilol (CAR), a β-adrenoceptor and α1-receptor blocker, has pH-dependent solubility, which greatly limits its oral bioavailability. In this work, …
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