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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198620/
The article will provide a brief and concise account of underlying principle of these polymeric vectors and their structural and functional modifications which were intended to serve different purposes to affect efficient therapeutic outcome of small-interfering RNA delivery.Author: Kaushik Singha, Ran Namgung, Won Jong Kim
https://www.researchgate.net/publication/51485823_Polymers_in_Small-Interfering_RNA_Delivery
This review will cover the current strategies that are being adopted to efficiently deliver small interfering RNA using nonviral vectors, including the use of polymers such as polyethylenimine ...
https://www.liebertpub.com/doi/10.1089/nat.2011.0293
Jun 29, 2011 · This review will cover the current strategies that are being adopted to efficiently deliver small interfering RNA using nonviral vectors, including the …Author: Kaushik Singha, Ran Namgung, Won Jong Kim
https://pubs.acs.org/doi/abs/10.1021/acsami.7b07337
Hydrophobization of cationic polymers, as an efficient strategy, had been widely developed in the structure of cationic polymer micelles to improve the delivery efficiency of nucleic acids. However, the distribution of hydrophobic segments in the polymer chains is rarely considered. Here, we have elaborated three types of hydrophobized polyethylene glycol (PEG)-blocked cationic polymers with ...Author: Changrong Wang, Lili Du, Junhui Zhou, Lingwei Meng, Qiang Cheng, Chun Wang, Xiaoxia Wang, Deyao Zhao...
https://www.ncbi.nlm.nih.gov/pubmed/23727920
Safe and effective delivery of small interfering RNA with polymer- and liposomes-based complexes. Kodama Y(1), Harauchi S, Kawanabe S, Ichikawa N, Nakagawa H, Muro T, Higuchi N, Nakamura T, Kitahara T, Sasaki H. Author information: (1)Department of Hospital Pharmacy, Nagasaki University Hospital, Nagasaki, Japan.Author: Yukinobu Kodama, Satoe Harauchi, Saki Kawanabe, Nobuhiro Ichikawa, Hiroo Nakagawa, Takahiro Muro, No...
https://www.liebertpub.com/doi/full/10.1089/nat.2011.0293
The article will provide a brief and concise account of underlying principle of these polymeric vectors and their structural and functional modifications which were intended to serve different purposes to affect efficient therapeutic outcome of small-interfering RNA delivery.Author: Kaushik Singha, Ran Namgung, Won Jong Kim
http://www.thno.org/v04p1211.htm
Functional Nanostructures for Effective Delivery of Small Interfering RNA Therapeutics . Cheol Am Hong 1, Yoon Sung Nam 1,2,3 . 1. Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 305-701, Republic of Korea; 2.
https://iopscience.iop.org/article/10.1088/0957-4484/27/12/125102/pdf
Small interfering RNA delivery through positively ... the polymers, PMMA has been chosen since it is bio-compatible and therefore suitable for in vitro and in vivo experiments. Moreover, since PMMA is a non-degradable polymer, it is possible to trace PMMA-based NPs duringAuthor: Luca Dragoni, Raffaele Ferrari, Monica Lupi, Alberto Cesana, Francesca Falcetta, Paolo Ubezio, Mauri...
https://link.springer.com/article/10.1007%2Fs12274-017-1946-z
Aug 02, 2018 · We report the development of a small interfering RNA (siRNA) delivery vector based on cationic perfluorocarbon nanoemulsions. ... Development of fluorinated polyplex nanoemulsions for improved small interfering RNA delivery and cancer therapy ... K., Wu, P. et al. Development of fluorinated polyplex nanoemulsions for improved small interfering ...Author: Gang Chen, Kaikai Wang, Pengkai Wu, Yixin Wang, Zhanwei Zhou, Lifang Yin, Minjie Sun, David Oupický,...
https://www.nature.com/articles/nmat3765
Oct 23, 2013 · Therapeutics based on small interfering RNA (siRNA), which in principle are able to reversibly silence any gene of interest, are under development for the …Author: Rosemary Kanasty, Joseph Robert Dorkin, Arturo Vegas, Arturo Vegas, Daniel Anderson
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