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https://www.hindawi.com/journals/apt/2019/1316249/
In the present investigation, an attempt was made to formulate timolol maleate (TML) loaded polymeric nanoparticles of flax seed gum (FX) and chitosan (CH) for ocular delivery using ionic gelation method. The process of nanoparticle preparation was optimized using 2-factor, 3-level central composite experimental design.Author: Neeraj Mittal, Gurpreet Kaur
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693026/
Jun 18, 2013 · Ocular drug transport barriers pose a challenge for drug delivery comprising the ocular surface epithelium, the tear film and internal barriers of the blood-aqueous and blood-retina barriers. Ocular drug delivery efficiency depends on the barriers and the clearance from the choroidal, conjunctival vessels and lymphatic.Author: Hong-Yan Zhou, Ji-Long Hao, Shuang Wang, Yu Zheng, Wen-Song Zhang
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617524/
Many intravitreal, polymeric drug delivery implants are already approved by the FDA. These include Retisert ... Vandervoort J, Ludwig A, Unlü N. Development and characterization of Cyclosporine A loaded nanoparticles for ocular drug delivery: Cellular toxicity, uptake, and kinetic studies. J Control Release. 2011; 151:286–94.
https://phosphorex.com/using-polymeric-nanoparticles-for-ocular-drug-delivery.html
Jul 08, 2014 · using polymeric nanoparticles for ocular drug delivery An application in which nanoparticles are successful is ocular drug delivery. In order to treat certain ocular diseases, it is necessary that the therapeutic agent penetrates the cornea.
https://www.sciencedirect.com/science/article/pii/S0168365909000595
Review Polymeric nanoparticulate system: A potential approach for ocular drug delivery 1. Introduction. The eye is characterized by its complex structure and high resistance... 2. Fabrication techniques of DNPs. Biodegradable nanoparticles for pharmaceutical use are prepared... 3. Physicochemical ...Author: Ramesh C. Nagarwal, Shri Kant, P.N. Singh, P. Maiti, J.K. Pandit
https://www.sciencedirect.com/science/article/abs/pii/S0168365909000595
Various efforts in ocular drug delivery have been made to improve the bioavailability and to prolong the residence time of drugs applied topically onto the eye. The potential use of polymeric nanoparticles as drug carriers has led to the development of many different colloidal delivery vehicles.
https://www.mdpi.com/2079-4991/10/4/720/htm
Ocular inflammation is one of the most prevalent diseases in ophthalmology, which can affect various parts of the eye or the surrounding tissues. Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, are commonly used to treat ocular inflammation in the form of eye-drops. However, their bioavailability in ocular tissues is very low (less than 5%). Therefore, drug delivery systems ...
https://www.slideshare.net/shivamthakore/polymeric-nanoparticles-a-novel-approach
Jul 26, 2013 · Polymeric nanoparticles A Novel Approach ... Corticoids release Anticancer therapy Crossing BBB Vaccines and gene therapy Diagnostic Ocular delivery 7/26/2013 Department of Pharmaceutical Technology, LJ institute of Pharmacy, Ahmedabad 37 ... “Biodegradable polymeric nanoparticles based drug delivery systems”,Colloids and Surfaces B ...
http://www.eurekaselect.com/99717
Nanoparticles have the potential to improve pharmacokinetics of ophthalmic drugs by surpassing the blood-aqueous and blood-retinal barriers. This review provides comprehensive and updated information on ocular drug delivery, with special emphasis on research articles and patents that involve the use of polymeric nanoparticles in treatment of vision-threatening diseases.Author: Sai H.S. Boddu
https://www.intechopen.com/books/application-of-nanotechnology-in-drug-delivery/polymer-nanoparticles-for-smart-drug-delivery
In approaches to drug delivery systems the route of administration is one of the crucial roles of drug targeting. These nanoparticles can be used for various routes, including oral, nasal, transdermal, parenterals, pulmonary, ocular, etc.Author: Devasier Bennet, Sanghyo Kim
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