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https://www.ncbi.nlm.nih.gov/pubmed/17168771
The polymeric micelles used for drug delivery in these examples have shown the abilities to attenuate toxicities, enhance delivery to desired biological sites and improve the therapeutic efficacy of active pharmaceutical ingredients.Author: S. R. Croy, G. S. Kwon
https://www.sciencedirect.com/science/article/pii/B9780128097175000063
Block copolymer micelles are one of the most promising classes of nanoparticles used in drug delivery. Block copolymers are formed by one homopolymer attached to one or more other homopolymers. These blocks are repeated throughout the structure of the copolymer …Author: Mohd Cairul Iqbal Mohd Amin, Adeel M. Butt, Muhammad W. Amjad, Prashant Kesharwani
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201986/
Oct 01, 2014 · While there have been many biodegradable polymeric nanoparticles synthesized for drug delivery, polymeric micelles have numerous advantages over other proposed colloidal delivery systems [4-7]. Many studies have shown the promise micelles have for drug delivery because they can be tailored for prolonged blood circulation time, cellular selectivity, and for their controlled release …Author: Alicia J. Sawdon, Ching-An Peng
https://www.sciencedirect.com/science/article/pii/S0169409X12002736
Compared to surfactant micelles, polymeric micelles are generally more stable, with a remarkably lowered critical micellar concentration (CMC), and have a slower rate of dissociation, allowing retention of loaded drugs for a longer period of time and, eventually, achieving higher accumulation of a drug at the target site . Furthermore, polymeric micelles have a size range of several tens of nanometers …Author: Kazunori Kataoka, Atsushi Harada, Yukio Nagasaki
https://www.unmc.edu/pharmacy/faculty/pharmaceutical-sciences/docs/v5.pdf
One of the first reported examples of unimolecular micelles suitable for drug delivery was a threearm star polymer - composed of mucic acid substituted with fatty acids as a lipophilic inner block and PEO as a hydrophilic outer block.
https://documents.pub/document/polymeric-micelles.html
WHY POLYMERIC MICELLES ARE ATRRACTIVE Polymeric micelles have gathered attention in drug & protein delivery due to : Biocompatibility Solubilization of hydrophobic moeities in micellar core More stable toward dilution & hence exhibit minimal cytotoxicity Enhanced blood circulation time suitable for i.v. administration drug delivery system Smart ...
http://www.authorstream.com/Presentation/kiranpatange75286-2128051-polymeric-micelles/
Apr 17, 2014 · Features of polyion complex polymeric micelles: Easy self association in aqueous medium Structured stability Sizes about 50 to 200 nm Prolonged circulation in the blood Entrap hydrophobic and hydrophilic compounds and charged particle Designed for drug delivery to brain tumor Eg . Dialysis Solution of drug and copolymer in organic...
https://www.slideshare.net/kiranpatange1/polymeric-micelles
Apr 17, 2014 · polymeric micelles as smart / intelligent drug delivery Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. If you continue browsing the site, you agree to the use of cookies on this website.
http://polymermicelles.com/
Additionally however, polymer micelles can be used for drug delivery as the hydrophobic interior has the capacity to hold drugs which are poorly soluble in aqueous solution. This web site discusses just a few uses of polymer micelles as well as the application of PolySciTech products to these uses.
https://www.slideshare.net/MeghrajSuryawanshi/seminar-polymeric-micelles
Mar 17, 2017 · CONCLUSION 04/03/2017 29 Polymeric Micelles are the used as carriers because of their characteristics. Polymeric micelles have simple method of preparation. Micelles get easily loaded with wide variety of poorly water soluble drug, resulting in enhanced the bioavalability. Micelles used to targeting the drug delivery. Targeting can also be ...
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