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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4113619/
Apr 04, 2014 · Polymeric micelles represent an effective delivery system for poorly water-soluble anticancer drugs. With small size (10–100 nm) and hydrophilic shell of PEG, polymeric micelles exhibit prolonged circulation time in the blood and enhanced tumor accumulation.Author: Yifei Zhang, Yixian Huang, Song Li
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7013754/
Jan 13, 2020 · A better understanding of the fate of polymeric micelles and cargo after cellular uptake might prove useful in optimizing the efficiency of the DDS. Furthermore, when the fate and intracellular trafficking of the polymeric micelles is known, various release or escape strategies could be implemented for optimal drug delivery into the cytosol.
https://www.sciencedirect.com/science/article/pii/B9780323509220000122
Polymer micelles are also designed to carry two or more anticancer drugs and can be targeted to cancer cells. This has helped in diminishing the toxic effects of the drugs on the normal healthy cells. Polymeric micelles have established themselves as model nanocarriers due to their favorable properties that are advantageous in drug, gene delivery,...Author: Radhika Raveendran
https://www.researchgate.net/publication/232084298_Polymeric_micelles_as_nanocarriers_for_drug_delivery
Polymeric micelles as nanocarriers for drug delivery. Polymeric micelles are built from amphiphilic polymers through self-assembly effects. Due to their unique core shell structure, small size and modifiable surface, polymeric micelles have been widely investigated as nanoscale drug delivery carriers.
https://link.springer.com/article/10.1208%2Fs12249-014-0113-z
Apr 04, 2014 · Polymeric micelles represent an effective delivery system for poorly water-soluble anticancer drugs. With small size (10–100 nm) and hydrophilic shell of PEG, polymeric micelles exhibit prolonged circulation time in the blood and enhanced tumor accumulation.Author: Yifei Zhang, Yixian Huang, Song Li
https://www.sciencedirect.com/science/article/pii/S1359029411000033
The hydrophobic core of micelles can solubilise poorly soluble drugs and partly protect the drug from the aqueous environment. Therefore, the use of polymeric micelles for oral drug delivery has been mainly restricted to the delivery of poorly soluble drugs.Author: Laurence Plapied, Nicolas Duhem, Anne des Rieux, Véronique Préat
https://www.ncbi.nlm.nih.gov/pubmed/17168771
The polymeric micelles used for drug delivery in these examples have shown the abilities to attenuate toxicities, enhance delivery to desired biological sites and improve the therapeutic efficacy of active pharmaceutical ingredients.Author: S. R. Croy, G. S. Kwon
https://www.sciencedirect.com/science/article/pii/S0163725806000933
Polymeric micelles, self-assemblies of block copolymers, are promising nanocarrier systems for drug and gene delivery. Until now, several micellar formulations of antitumor drugs have been intensively studied in preclinical and clinical trials, and their utility has been demonstrated.Author: Nobuhiro Nishiyama, Kazunori Kataoka
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634382/
Oct 05, 2017 · Nanoconjugation-based combined drug delivery of doxorubicin and cisplatin for the treatment of locally advanced breast tumor with enhanced efficiency and reduced toxicity was another successful antitumor drug combination study performed by Cohen et al.122 Doxorubicin–cisplatin-loaded nanocarriers were administered subcutaneously, and their therapeutic effect was achieved as a result of the cleavage of hyaluronan in the lymph, leading to the transport of free drug …Author: Fakhar ud Din, Waqar Aman, Izhar Ullah, Omer Salman Qureshi, Omer Mustapha, Shumaila Shafique, Alam ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951761/
Apr 24, 2016 · Carriers have used in drug delivery systems have consisted of the simplest form of structures with sizes in the nm or µm ranges, made of polymers (polymeric carriers, micelles or dendrimers), lipids (liposomes), solid lipid carriers, gold carriers, …Author: Hadi Khodabandehloo, Hamid Zahednasab, Asghar Ashrafi Hafez
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