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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438887/
Polymers for Drug Delivery Systems. ... a truly intelligent delivery system must address the need for specific targeting, intracellular transport, and biocompatibility while integrating elements of responsive behavior to physiological environments and recognitive feedback control. ... the latest drug delivery research using polymeric materials ...Author: William B. Liechty, David R. Kryscio, Brandon V. Slaughter, Nicholas A. Peppas
https://www.ncbi.nlm.nih.gov/pubmed/17168771
Polymeric micelles are nanoscopic core/shell structures formed by amphiphilic block copolymers. Both the inherent and modifiable properties of polymeric micelles make them particularly well suited for drug delivery purposes.Author: S. R. Croy, G. S. Kwon
https://www.sciencedirect.com/topics/nursing-and-health-professions/drug-delivery-system
Drug Delivery System. A drug delivery system (DDS) is defined as a formulation or a device that enables the introduction of a therapeutic substance into the body and improves its efficacy and safety by controlling the rate, time, and place of release of drugs in the body.
https://www.mddionline.com/polymers-controlled-drug-delivery
Drug delivery from a typical matrix drug delivery system. For the reservoir systems shown in Figures 3a and 3b, the drug delivery rate can remain fairly constant. In this design, a reservoir whether solid drug, dilute solution, or highly concentrated drug solution within a polymer matrix is surrounded by a film or membrane of a rate-controlling ...
https://www.sciencedirect.com/science/article/pii/S016836591101114X
Polymeric micelles (PM) system, as an efficient drug carrier, has received growing scientific attention in recent years owing to its solubilization, selective targeting, P-glycoprotein inhibition and altered drug internalization route and subcellular localization properties.Author: Jian Gong, Mei Wan (陳美婉) Chen, Ying (鄭穎) Zheng, Sheng Peng Wang, Yi Tao (王一濤) Wang
https://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma-Aldrich/Method/1/polymeric-drug-delivery-techniques-web.pdf
hydrophobic drugs by encapsulation in a drug delivery carrier or by conjugation with a polymer. Selecting a Polymeric Drug Delivery System There are three main categories of polymeric drug delivery systems; colloidal carriers (micro, nanoparticles, micelles, micro/nanogels), implantable networks or hydrogels, and polymer drug conjugates.
https://www.hindawi.com/journals/jdd/2013/340315/
Oral administration is the most commonly used and readily accepted form of drug delivery; however, it is find that many drugs are difficult to attain enough bioavailability when administered via this route. Polymeric micelles (PMs) can overcome some limitations of the oral delivery acting as carriers able to enhance drug absorption, by providing (1) protection of the loaded drug from the harsh ...Author: Wei Xu, Peixue Ling, Tianmin Zhang
https://pubs.acs.org/doi/abs/10.1021/acsabm.9b00097
Targeted tumor cell killing using polymeric micelles with active targeting strategies has been demonstrated to be effectively therapeutic for liver cancers. To implement this strategy, enhancing the cellular uptake of the drug delivery system with targeted anticancer drugs, such as doxorubicin toward nuclear targeting, is of vital importance for increasing drug efficiency and reducing the ...Author: Qiaochu Hua, Zhe Qiang, Maoquan Chu, Donglu Shi, Donglu Shi, Jie Ren
https://www.sigmaaldrich.com/materials-science/drug-delivery/drug-delivery-welcome.html
This guide is intended to provide an overview of polymeric drug delivery systems as well as provide the corresponding example formulation protocols and product information required to utilize these techniques in …
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