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https://www.ncbi.nlm.nih.gov/pubmed/17168771
Polymeric micelles are nanoscopic core/shell structures formed by amphiphilic block copolymers. Both the inherent and modifiable properties of polymeric micelles make them particularly well suited for drug delivery purposes.Author: S. R. Croy, G. S. Kwon
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438887/
The majority of responsive polymers for drug delivery can be broadly categorized as hydrogels, micelles, polyplexes, or polymer-drug conjugates, which are covered in more detail below. Hydrogels are hydrophilic (co)polymeric networks capable of imbibing large amounts of water or biological fluids . Physical or covalent crosslinks render ...Author: William B. Liechty, David R. Kryscio, Brandon V. Slaughter, Nicholas A. Peppas
https://www.sciencedirect.com/science/article/pii/S1369527409001805
Particulate vaccine delivery is a growing technology elevated by the recent successful application and commercialization of particle-based vaccines. The use of particles as successful vaccine delivery tools poses a number of questions regarding the specific role of the particle in vaccination and stimulation of an immune response.Author: Allison C Rice-Ficht, Angela M Arenas-Gamboa, Angela M Arenas-Gamboa, Melissa M Kahl-McDonagh, Thoma...
https://pubs.acs.org/doi/10.1021/jacs.9b12759
Nanocarrier-mediated protein delivery is a promising strategy for fundamental research and therapeutic applications. However, the efficacy of the current platforms for delivery into cells is limited by endosomal entrapment of delivered protein cargo with concomitantly inefficient access to the cytosol and other organelles, including the nucleus. We report here a robust, versatile polymeric ...Author: Yi-Wei Lee, David C. Luther, Ritabrita Goswami, Taewon Jeon, Vincent Clark, James Elia, Sanjana Gopa...
https://www.sciencedirect.com/science/article/pii/B9780123969835000211
In recent years, significant advances have been made in drug delivery systems through the use of both natural and synthetic polymers. Polymers (with desired physicochemical properties) can be used in the manufacture of tablets, implants, microspheres, nanoparticles, drug-eluting stents, in situ forming gels, and polymeric scaffolds (for tissue engineering) to achieve the goal of controlled ...Author: Bing Gu, Diane J. Burgess
http://polymermicelles.com/
Additionally however, polymer micelles can be used for drug delivery as the hydrophobic interior has the capacity to hold drugs which are poorly soluble in aqueous solution. This web site discusses just a few uses of polymer micelles as well as the application of PolySciTech products to these uses. Why would a copolymer form a micelle?
https://www.sigmaaldrich.com/materials-science/drug-delivery/drug-delivery-welcome.html
This guide is intended to provide an overview of polymeric drug delivery systems as well as provide the corresponding example formulation protocols and product information required to utilize these techniques in …
https://pubs.acs.org/doi/full/10.1021/jacs.9b12759
Nanocarrier-mediated protein delivery is a promising strategy for fundamental research and therapeutic applications. However, the efficacy of current platforms for delivery into cells is limited by endosomal entrapment of delivered protein cargo, with concomitantly inefficient access to the cytosol and other organelles, including the nucleus. We report here a robust, versatile polymeric ...Author: Yi-Wei Lee, David C. Luther, Ritabrita Goswami, Taewon Jeon, Vincent Clark, James Elia, Sanjana Gopa...
https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201914751
Jan 29, 2020 · To alleviate this burden, we herein report systemic ASO delivery to the brain by crossing the blood–brain barrier using glycemic control as an external trigger. Glucose‐coated polymeric nanocarriers, which can be bound by glucose transporter‐1 expressed on the brain capillary endothelial cells, are designed for stable encapsulation of ...Author: Hyun Su Min, Hyun Jin Kim, Mitsuru Naito, Satomi Ogura, Kazuko Toh, Kotaro Hayashi, Beob Soo Kim, Sh...
https://www.researchgate.net/publication/286542347_Polymeric_Materials_in_Drug_Delivery
These delivery systems (such as liposomes, emulsions, nanocrystals, and polymeric nanocarriers) have been extensively used to improve bioavailability, prolong pharmacological effects, achieve ...
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