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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476746/
Introduction. Polymersomes, which also can be called polymeric vesicles, have attracted scientists' interests in recent years. Compared to other nanometer scale self-assembling delivery systems, such as polymer micelles, nanoparticles and nanogels, polymersomes provide a more stable condition for the storage of drugs, especially for nanoscopic emulsions (Asano et al., 2016).Author: Yi Zhao, Xiaoming Li, Xiaotian Zhao, Yunqi Yang, Hui Li, Xinbo Zhou, Weien Yuan
https://www.sciencedirect.com/science/article/pii/S0079670016300259
Polymer vesicles, also known as polymersomes, are finding increasing applications in biomedical field, including drug delivery, gene therapy, magnetic resonance imaging, theranostics, etc. This is due to their intrinsic hollow nanostructure and compartmentalized domains with diverse functionalities.Author: Yunqing Zhu, Bo Yang, Shuai Chen, Jianzhong Du
https://www.sciencedirect.com/science/article/pii/S0169409X1830262X
Liposomes are often considered the archetype of many drug delivery vesicles, originally described half-a-century ago and widely considered the first “nanoscale drug” approved for clinical use [7,8]. Polymersomes are closely related vesicles, assembled from polymers instead of lipids and first reported in the mid-1990s [10,11].Author: Ulrike Kauscher, Margaret N. Holme, Mattias Björnmalm, Molly M. Stevens
https://pubs.acs.org/doi/abs/10.1021/ma3015728
Oct 02, 2012 · Wenqin Chen, Jianzhong Du. Ultrasound and pH Dually Responsive Polymer Vesicles for Anticancer Drug Delivery. Scientific Reports 2013, 3 (1) DOI: 10.1038/srep02162. Shaojian Lin, Patrick Theato. CO 2 -Responsive Polymers.Author: Jianzhong Du, Lang Fan, Qiuming Liu
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470373/
Polymersomes are stable vesicles prepared from amphiphilic polymers and are more stable compared with liposomes. Although these nanovesicles have many attractive properties for in vitro/in vivo applications, liposome-based drug delivery systems are still prevalent in the market. In order to expedite the translational potential and to provide medically valuable formulations, the polymersomes ...Author: Tayebeh Anajafi, Sanku Mallik
https://science.sciencemag.org/content/297/5583/967.full
Future applications of polymer vesicles will rely on exploiting unique property-performance relations, but results to date already underscore the fact that biologically derived vesicles are but a small subset of what is physically and chemically possible. ... Adv. Drug Delivery Rev. 32, 3 (1998).
https://pubs.acs.org/doi/10.1021/ar200036k
May 24, 2011 · Microparticle templating as a route to nanoscale polymer vesicles with controlled size distribution for anticancer drug delivery. Journal of Colloid and Interface Science 2017, 508, 145-153. DOI: 10.1016/j.jcis.2017.08.049. Omer F. Mutaf, Yasutaka Anraku, Akihiro Kishimura, Kazunori Kataoka.Author: Pascal Tanner, Patric Baumann, Ramona Enea, Ozana Onaca, Cornelia Palivan, Wolfgang Meier
https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.2042-7158.1998.tb06185.x
The hydrophilic spacer was thought to be necessary to decouple the random motion of the polymer backbone from the ordered amphiphiles that make up the vesicle membrane. However, stable polymeric vesicles for use in drug delivery have been prepared from a modified carbohydrate polymer, palmitoyl glycol chitosan, without this specific architecture.Author: Ijeoma F. Uchegbu, Andreas G. Schätzlein, Andreas G. Schätzlein, Laurence Tetley, Laurence Tetley, A...
https://www.researchgate.net/publication/277705367_Polymer_Vesicles
Polymer vesicles (or polymersomes) which have hydrophilic coronas expressed on the hydrophobic membrane have attracted growing attention in recent years due to their potential applications in ...Author: Jianzhong Du
https://www.sigmaaldrich.com/technical-documents/articles/material-matters/polymersomes-for-drug-delivery.html
An alternate method of pH-stimulated drug delivery from polymersome vesicles, involves linking the polymer blocks through a pH-sensitive bond, such as an imine, hydrazone, or acetal. 4 Upon exposure to acidic conditions, the link between the hydrophilic and hydrophobic block degrades, leading to the breakdown of the polymersome and release of ...
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