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https://www.researchgate.net/publication/266319032_Polymer_Nanoparticles_for_Smart_Drug_Delivery
Rapid cellular uptake with reduced toxicity remains a great challenge for efficient and safe drug delivery , nanoparticles as drug delivery system may be prepared with effective control of ...
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
The green chemistry route of designing nanoparticles loaded with drugs is widely encouraged as it minimises the hazardous constituents in the biosynthetic process. Thus, using green nanoparticles for drug delivery can lessen the side-effects of the medications . Moreover, adjustments in nanostructures size, shape, hydrophobicity, and surface ...
https://www.mdpi.com/2079-4983/10/1/4
Polymer nanoparticles (NPs) represent one of the most innovative non-invasive approaches for drug delivery applications. NPs main objective is to convey the therapeutic molecule be they drugs, proteins, or nucleic acids directly into the target organ or tissue. Many polymers are used for the synthesis of NPs and among the currently most employed materials several biocompatible synthetic ...
https://en.wikipedia.org/wiki/Nanoparticle_drug_delivery
Nanoparticle drug delivery systems are engineered technologies that use nanoparticles for the targeted delivery and controlled release of therapeutic agents. The modern form of a drug delivery system should minimize side-effects and reduce both dosage and dosage frequency. Recently, nanoparticles have aroused attention due to their potential application for effective drug delivery.
https://pubs.acs.org/doi/10.1021/nn9014032
We report the synthesis of novel acid-responsive therapeutic nanoparticles (NPs) with sub-100 nm size consisting of polymer−cisplatin conjugates. The uniqueness of these drug delivery polymeric NPs lies in the covalent conjugation of each cisplatin drug to the hydrophobic segment of two biocompatible diblock copolymer chains through a hydrazone bond, resulting in highly differential drug ...
https://www.cell.com/heliyon/fulltext/S2405-8440(19)31154-5
May 15, 2019 · Chitosan, a natural carbohydrate polymer, has long been investigated for drug delivery and medical applications due to its biodegradability, biocompatibility and low toxicity. The micro/nanoparticulate forms of chitosan are reported to enhance the efficiency of drug delivery with better physicochemical properties including improved solubility and bioavailability. This polymer is …
https://pubs.acs.org/doi/10.1021/acsnano.5b01433
Considerable progress in the synthesis and technology of hydrogels makes these materials attractive structures for designing controlled-release drug delivery systems. In particular, this review highlights the latest advances in nanocomposite hydrogels as drug delivery vehicles. The inclusion/incorporation of nanoparticles in three-dimensional polymeric structures is an innovative means for ...
https://www.researchgate.net/publication/277312681_Smart_Polymers_Drug_Delivery
Smart Polymers: Drug Delivery. ... Such “smart” nanoparticles can, therefore, help limit the exposure of healthy tissue to cytotoxic drugs. ... This article reviews the state-of-the art in ...
https://link.springer.com/chapter/10.1007%2F978-3-319-20206-8_7
Halidi M, Shahbazi M-A, Peymani P (2010) Application of smart polymers in drug delivery. In: Li S, Tiwari A, Prabaharam M, Aryal S (eds) Smart polymer materials for biomedical applications. Nova Science Publishers Inc., New York, pp 359–382 Google Scholar
https://nanomedicine.pharmaceuticalconferences.com/usa/
Sessions/Tracks. Track 1: Nanoparticles and Nanomedicine Nanomedicine is a branch of medicine that applies the knowledge and tools of nanotechnology in the prevention and treatment of diseases. Nanomedicine involves the use of nanoscale materials, such as biocompatible nanoparticles and Nano robots, for diagnosis, delivery, sensing or actuation purposes in a living organism.
https://www.cell.com/trends/pharmacological-sciences/pdf/S0165-6147(18)30100-7.pdf
in tumor-targeted drug delivery. PEGylation: a technique of covalent or noncovalent attachment of polyethylene glycol (PEG), a flexible hydrophilic polymer, onto drugs or nanoparticles. strategies It is widely used in drug delivery for drug solubilization, nanoparticle stabilization, prolonged blood circulation, and tumor targeting. P ...
https://www.nature.com/articles/s41392-017-0004-3
Mar 16, 2018 · Dual anticancer drug-loaded antibacterial smart polymer nanohybrids have the potential to be used for combination cancer therapy. ... V. et al. Mesoporous silica nanoparticles as drug delivery ...
https://www.hindawi.com/journals/jnm/2011/408675/
Sep 20, 2010 · Overall, passive polymer drug carriers have not demonstrated increased therapeutic efficacy due to lack of intercellular and localized, rapid drug delivery [28–30]. Current research has thus focused on advancing these polymer vehicles with “smart” technologies that are responsive to environmental stimuli.
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Drugs have long been used to improve health and extend lives. The practice of drug delivery has changed dramatically in the past few decades and even greater changes are anticipated in …
https://onlinelibrary.wiley.com/doi/full/10.1002/cphc.201800018
Mar 24, 2018 · Mesoporous silica nanoparticles (MSNs) are one of the most promising drug‐delivery systems. Functionalization of MSN surfaces with responsive polymer brushes leads to intelligent and controllable dru...
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