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https://www.onlinelibrary.wiley.com/doi/10.1002/marc.201800917
Acid labile imine bonds (Figure 5B) have also been investigated as pH‐responsive linkages to design drug loaded nanoparticles. 60 In 2014, the Zheng group reported a hydrogen bonding strategy to load hydrophobic drug melphalan into core‐shell micelles with carboxymethyl chitosan polymer as the shell. Pyridyl moieties were attached to the polymers via imine linkages and hydrogen bonds were then …Author: Nayeleh Deirram, Changhe Zhang, Sarah S. Kermaniyan, Angus P. R. Johnston, Georgina K. Such
https://www.sciencedirect.com/science/article/pii/B9780081019979000151
Nanostructures of responsive polymers have shown great promise in biomedical field especially in designing drug delivery systems. The present chapter enlightens one on the various significant features of polymer nanoparticles being used as responsive drug delivery systems.Author: Rajesh K. Saini, Laxmi P. Bagri, Anil K. Bajpai, Abhilasha Mishra
https://www.ncbi.nlm.nih.gov/pubmed/20217595
The use of biodegradable polymeric nanoparticles (NPs) for controlled drug delivery has shown significant therapeutic potential. Concurrently, targeted delivery technologies are becoming increasingly important as a scientific area of investigation.Author: Juliana M. Chan, Pedro M. Valencia, Liangfang Zhang, Robert Langer, Omid C. Farokhzad
https://www.intechopen.com/books/application-of-nanotechnology-in-drug-delivery/polymer-nanoparticles-for-smart-drug-delivery
The smart drug delivery system enhances the polymer nanoparticle better stage to their therapy regimen. They are drug carriers of natural, semi-synthetic, and synthetic polymeric nature at the nano-scale to micro-scale range. The polymeric particles are collectively named as spheres and capsules.Author: Devasier Bennet, Sanghyo Kim
https://www.horiba.com/fileadmin/uploads/Scientific/Documents/PSA/Webinar_Slides/AP028.pdf
PLA Nanoparticles for Drug Delivery Targeting ligand provides recognition, enabling targeted nanoparticles to identify and bind to their intended target site. Surface functionalization shields targeted nanoparticles from the immune system. Polymer matrix encapsulates payload molecules in a matrix of biodegradable polymers . Therapeutic payloads include
https://www.sciencedirect.com/science/article/pii/S0928493115305981
A targeted delivery system based on the polymeric nanoparticles as a drug carrier represents a marvelous avenue for cancer therapy. The pivotal characteristics of this system include biodegradability, biocompatibility, non-toxicity, prolonged circulation and a wide payload spectrum of a therapeutic agent.Author: Farha Masood
https://www.researchgate.net/publication/41850553_Polymeric_Nanoparticles_for_Drug_Delivery
The use of biodegradable polymeric nanoparticles (NPs) for controlled drug delivery has shown significant therapeutic potential. Concurrently, targeted delivery technologies are becoming...
http://www.nanoparticles.org/pdf/Pun.pdf
Advantages of Nanoparticles for Drug Delivery University of Illinois, Urbana-Champagne Examples of Nanoparticles for Drug Delivery Liposomal Amphoterin, sold by Gilead (Ambisome) and Enzon (Abelcet) ~$200 Million in Ambisome sales in 2003. Gilead Sciences • Amphotericin treats fungal and parasite infection
https://www.powershow.com/viewht/7aa0f-ZDc1Z/Nanotechnology_Based_Drug_Delivery_powerpoint_ppt_presentation
Mutate chemically labile amino acids to other amino acids, however, antigenicity ... PowerPoint PPT presentation free to view. The Use of Nanoparticles in Drug Delivery Systems - Doxil is the drug doxorubicin HCl encapsulated in an antibody linked PEGylated liposome ...
https://www.slideshare.net/shivamthakore/polymeric-nanoparticles-a-novel-approach
Jul 26, 2013 · Introduction: Polymeric Nanoparticles • What are PNP’s? They are solid colloidal particles ranging in size from 10 to 1000 nm (1µm). Drug may be dissolved, entrapped, encapsulated or attached to a nanoparticle matrix . Because these systems have very high surface areas, drugs may also be adsorbed on their surface. Polymer-based nanoparticles effectively carry drugs, proteins …
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