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https://www.sciencedirect.com/science/article/pii/S0939641105000147
Polyethylenimine-based non-viral gene delivery systems ... In view of the great diversity within the field of non-viral gene delivery, here we chose to focus on polyethylenimine-based transfection vehicles, including strategies for their optimization and the observed effects thereof. ... M.E. DavisNon-viral gene delivery systems.Author: Uta Lungwitz, Miriam Breunig, Torsten Blunk, Achim Göpferich
https://www.ncbi.nlm.nih.gov/pubmed/15939236
Polyethylenimine-based non-viral gene delivery systems. Lungwitz U(1), Breunig M, Blunk T, Göpferich A. Author information: (1)Department of Pharmacy and Chemistry, Pharmaceutical Technology Unit, University of Regensburg, Regensburg, Germany.Author: Uta Lungwitz, Miriam Breunig, Torsten Blunk, Achim Göpferich
https://www.sciencedirect.com/science/article/abs/pii/S0939641105000147
Polyethylenimine-based non-viral gene delivery systems ... In recent years, PEI-based non-viral vectors have been locally or systemically delivered, mostly to target gene delivery to tumor tissue, the lung or liver. This requires strategies to efficiently shield transfection polyplexes against non-specific interaction with blood components ...Author: Uta Lungwitz, Miriam Breunig, Torsten Blunk, Achim Göpferich
https://www.researchgate.net/publication/7803545_Polyethylenimine-based_non-viral_gene_delivery_systems
The other popular way to deliver NAs into mammalian cells relies on the use of gene delivery carriers, also known as systems or vectors, which can be further categorized into viral and non-viral ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171788/
Jul 03, 2018 · The meaning of gene therapy is the delivery of DNA or RNA to cells for the treatment or prevention of genetic disorders. The success rate of gene therapy depends on the progression and safe gene delivery system. The vectors available for gene therapy are divided into viral and non-viral systems.Author: Abbas Zakeri, Mohammad Amin Jadidi Kouhbanani, Nasrin Beheshtkhoo, Vahid Beigi, Seyyed Mojtaba Mousa...
https://www.nature.com/articles/s41598-020-61465-6
Mar 12, 2020 · Clustered regularly interspaced short palindromic repeats-associated protein (CRISPR/Cas9) system has become a revolutionary tool for gene editing. Since viral delivery systems have significant ...Author: S. S. Rohiwal, N. Dvorakova, J. Klima, M. Vaskovicova, F. Senigl, M. Slouf, E. Pavlova, P. Stepanek,...
http://europepmc.org/abstract/MED/15939236
Jul 01, 2005 · Gene therapy has become a promising strategy for the treatment of many inheritable or acquired diseases that are currently considered incurable. Non-viral vectors have attracted great interest, as they are simple to prepare, rather stable, easy to modify and relatively safe, compared to viral vectors.Author: Uta Lungwitz, Miriam Breunig, Torsten Blunk, Achim Göpferich
https://www.researchgate.net/publication/323211203_Non-viral_gene_delivery_systems_for_tissue_repair_and_regeneration
One of the current state-of-the-art methods for TRR is gene therapy. Non-viral gene delivery systems (nVGDS) have great potential for TE and have several advantages over viral delivery including ...
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