Polyethylenimine And Its Role In Gene Delivery

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Polyethylenimine-based nanocarriers in co-delivery of drug ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171788/
    Jul 03, 2018 · Nanocarriers have an important role in delivery of drug-gene combinations to cancer cells . ... [52] Dongjie S, Wu H, Shen F, et al. Carbon dioxide-modified polyethylenimine as a novel gene delivery vector and its in vitro validation. J Biomater Appl. 2017; 31 (9):1257–1266.Author: Abbas Zakeri, Mohammad Amin Jadidi Kouhbanani, Nasrin Beheshtkhoo, Vahid Beigi, Seyyed Mojtaba Mousa...

Polyethylenimine based magnetic nanoparticles mediated non ...

    https://www.nature.com/articles/s41598-020-61465-6
    Mar 12, 2020 · Polyethylenimine based magnetic nanoparticles mediated non-viral CRISPR/Cas9 system for genome editing ... we next focused our attention to test the potential of …Author: S. S. Rohiwal, N. Dvorakova, J. Klima, M. Vaskovicova, F. Senigl, M. Slouf, E. Pavlova, P. Stepanek,...

Synthesis and Evaluation of Tetramethylguanidinium ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4017721/
    Apr 24, 2014 · 1. Introduction. Gene therapy has shown promising results in the treatment of both inherited and acquired genetic diseases; however, lack of a safe and efficient nucleic acid delivery system has hampered its widespread use [1–3].Recently, nonviral vector-based nucleic acid delivery has gained great interest due to ease of its preparation, production, modification, low immunogenicity, and ...Author: Manohar Mahato, Santosh Yadav, Pradeep Kumar, Ashwani Kumar Sharma

Different synergistic roles of small polyethylenimine and ...

    https://www.sciencedirect.com/science/article/pii/S0168365902004893
    Different synergistic roles of small polyethylenimine and Dosper in gene delivery ... K.K. Wu, A.G. MikosPoly(ethylenimine) and its role in gene delivery. J. Control. Release, 60 (1999), pp. 149-160. Google Scholar. A. Kichler, C. Leborgne ... A. UrttiInteractions of polymeric and liposomal gene delivery systems with extracellular ...Author: Pasi Lampela, Matti Elomaa, Marika Ruponen, Arto Urtti, Pekka T Männistö, Atso Raasmaja

(PDF) Godbey, WT, Wu, KK and Mikos, AG. Poly(ethylenimine ...

    https://www.researchgate.net/publication/12874914_Godbey_WT_Wu_KK_and_Mikos_AG_Polyethylenimine_and_its_role_in_gene_delivery_J_Control_Release_60_149-160
    Godbey, WT, Wu, KK and Mikos, AG. Poly(ethylenimine) and its role in gene delivery. J Control Release 60: 149-160

A simple and rapid nonviral approach to efficiently ...

    https://www.nature.com/articles/nprot.2012.038
    Apr 19, 2012 · This protocol outlines steps for optimizing the transfection of adherent primary mammalian cells using the readily available off-the-shelf cationic polymer, 25 …Author: Charlie Yu Ming Hsu, Hasan Uludağ

Poly(ethylenimine) and its role in gene delivery ...

    https://www.sciencedirect.com/science/article/pii/S0168365999000905
    The protonability of PEI has already been mentioned as important to PEI’s success as a gene delivery vehicle. A useful descriptor of PEI’s protonability is its pK a, which has remained elusive because rigorous analysis of experimental data to obtain PEI’s pK a would require one to include an ionization constant for every amine group .The number of amine groups can easily exceed 1000 ...Author: W.T. Godbey, Kenneth K. Wu, Antonios G. Mikos

Polyethylenimine, linear average Mn 10,000, PDI ≤1.3 ...

    https://www.sigmaaldrich.com/catalog/product/aldrich/765090
    Polyethylenimine (linear) is a versatile cationic polymer with a high transfection efficiency. It is used as a gene delivery reagent. It is a non-lipid polycation that can be used to transfect oligonucleotides and plasmid into cells in vitro and in vivo. Packaging 1 g in glass bottle

Polyethylenimine DNA solid particles for gene delivery ...

    https://www.researchgate.net/publication/5805510_Polyethylenimine_DNA_solid_particles_for_gene_delivery
    Polyethylenimine (PEI), a cationic polymer, was used to develop a non-viral vector for gene delivery. A simple, reproducible process is described with which to condense plasmid DNA with PEI.

Polyethylenimine, branched average Mw ~25,000 by LS ...

    https://www.sigmaaldrich.com/catalog/product/aldrich/408727
    Application Used as a polyelectrolyte multilayer on charged surfaces to provide a biocompatible coating on surfaces. Detergents, adhesives, water treatment, printing inks, dyes, cosmetics, and paper industry, adhesion promoter, lamination primer, fixative agent, flocculant, cationic dispersant, stability enhancer, surface activator, chelating agent, scavenger for aldehydes and oxides.

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