Polyethylene Glycol Drug Delivery

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Facile synthesis of ultrasmall polydopamine-polyethylene ...

    https://avs.scitation.org/doi/10.1116/1.5042640
    Very small polydopamine (PDA) polyethylene glycol (PEG) crosslinked copolymer (PDA-PEG) nanoparticles have been prepared following a convenient one …

What is Polyethylene Glycol (PEG)? - News-Medical.net

    https://www.news-medical.net/life-sciences/What-is-Polyethylene-Glycol-(PEG).aspx
    Feb 04, 2020 · Polyethylene glycol (PEG) is a biocompatible, synthetic, hydrophilic polyether compound that has many applications, mostly in the medical industry. ... PEG hydrogels are also used in drug delivery ...

Polyethylene Glycol Derivatives (PEGs),Drug Delivery ...

    https://www.sinopeg.com/about-us_d1
    SINOPEG is a dynamic science company dedicated to drug delivery systems (DDS). As a leading company in polyethylene glycol derivatives (PEGs), we are also specialized in the R&D of long acting biopharmaceuticals, developing and manufacturing of block copolymers, lipids for drug delivery, medical devices, bio-engineering, and other broad uses.

Engineering of Biomaterials for Drug Delivery Systems ...

    https://www.elsevier.com/books/engineering-of-biomaterials-for-drug-delivery-systems/parambath/978-0-08-101750-0
    Engineering of Biomaterials for Drug Delivery Systems: Beyond Polyethylene Glycol examines the combined issues of PEGylation and viable biomaterials as alternatives. With a strong focus on polymeric biomaterials, the book first reviews the major issues associated with PEGylation and its use in vivo.

Polyethylene Glycol-Coated Gold Nanoparticles as DNA and ...

    https://www.hindawi.com/journals/jnm/2019/5982047/
    It was shown that the polyethylene glycol-coated gold nanoparticles presented transfection efficiency and cell uptake greater than 45% in each case. These results suggest that the synthetized gold nanoparticles coated with polyethylene glycol could be used successfully and safely as DNA and drug delivery systems.

Poly(ethylene glycol)-Prodrug Conjugates: Concept, Design ...

    https://www.hindawi.com/journals/jdd/2012/103973/
    Poly(ethylene glycol) (PEG) is the most widely used polymer in delivering anticancer drugs clinically. PEGylation (i.e., the covalent attachment of PEG) of peptides proteins, drugs, and bioactives is known to enhance the aqueous solubility of hydrophobic drugs, prolong circulation time, minimize nonspecific uptake, and achieve specific tumor targetability through the enhanced permeability and ...

Polyethylene Glycol Properties and The Applications in ...

    http://formulation.vinensia.com/2011/11/polyethylene-glycol-properties-and.html
    Polyethylene glycols are chemically stable in air and in solution although grades with a molecular weight less than 2000 are hygroscopic. Polyethylene glycols do not support microbial growth, nor do they become rancid. Polyethylene glycols and aqueous polyethylene glycol solutions can be sterilized by autoclaving, filtration or gamma irradiation.

Solubility enhancement of hydrophobic drugs via drug ...

    https://www.sigmaaldrich.com/technical-documents/articles/materials-science/plga-drug-delivery.html
    Solubility enhancement of hydrophobic drugs via drug-loaded micelles using biodegradable PEG- polyester diblock copolymers The requirement for large quantities of saline to dissolve such materials limits their clinical use, and one solution for this problem that has recently generated interest is the formation of drug-loaded micelles.

Dense hydroxyl polyethylene glycol dendrimer targets ...

    https://advances.sciencemag.org/content/6/4/eaay8514.full
    Poor transport of neuropharmaceutics through central nervous system (CNS) barriers limits the development of effective treatments for CNS disorders. We present the facile synthesis of a novel neuroinflammation-targeting polyethylene glycol–based dendrimer (PEGOL-60) using an efficient click chemistry approach. PEGOL-60 reduces synthetic burden by achieving high hydroxyl surface density …

PEGylation - Wikipedia

    https://en.wikipedia.org/wiki/Pegylated
    PEGylation (often styled pegylation) is the process of both covalent and non-covalent attachment or amalgamation of polyethylene glycol (PEG, in pharmacy called macrogol) polymer chains to molecules and macrostructures, such as a drug, therapeutic protein or vesicle, which is then described as PEGylated (pegylated).

Polypropylene glycol C6H14O3 - PubChem

    https://pubchem.ncbi.nlm.nih.gov/compound/Polypropylene-glycol
    In the medical field they find applications as protective bandages, in drug delivery systems, in organ preservation, in dental compositions, and as a fat substitute. Gagnon SD; Kirk-Othmer Encyclopedia of Chemical Technology. ... (incl polypropylene glycol, polyethylene glycol, and propylene oxide-ethylene oxide copolymers), 65% were used in ...

MMP-8-Responsive Polyethylene Glycol Hydrogel for ...

    https://journals.sagepub.com/doi/full/10.1177/0022034519831931
    Currently available drug delivery systems for oral diseases suffer from short retention time and poor local concentrations at the target site. A biodegradable stimulus-responsive hydrogel was synthesized in the present study to evaluate its application as an environmentally sensitive carrier for on-demand intraoral drug delivery.

Pluronic F127 and D-α-Tocopheryl Polyethylene Glycol ...

    https://www.nature.com/articles/s41598-017-03123-y
    A novel polymeric mixed micelle composed of Pluronic F127 and D-α-tocopheryl polyethylene glycol succinate (TPGS) was developed to improve the delivery of fluorescent dyes and protein across the ...

Polyethylene Glycol Pharma Excipients

    https://www.pharmaexcipients.com/petrochemicals/polyethylene-glycol/
    Polyethylene Glycol. Pharma Excipients. Polyethylene Glycol. Coating. ... Solidification of carvedilol loaded SMEDDS by swirling fluidized bed pellet coating Self-(micro)emulsifying drug delivery systems (S(M)EDDS) have emerged as effective vehicles for enhancing bioavailability of poorly water soluble drugs, however solidification of the ...

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