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https://pubs.acs.org/doi/10.1021/bc010103m
Apr 24, 2002 · We evaluated various dendritic architectures composed of a polyester dendritic scaffold based on the monomer unit 2,2-bis(hydroxymethyl)propanoic acid for their suitability as drug carriers both in vitro and in vivo. These systems are both water soluble and nontoxic.Author: Omayra L. Padilla De Jesus, Henrik R. Ihre, Lucie Gagne, Jean M. J. Frechet, Francis C. Szoka
https://pubs.acs.org/doi/10.1021/bc010102u
Apr 24, 2002 · Polyester Dendritic Systems for Drug Delivery Applications: Design, Synthesis, and CharacterizationAuthor: Henrik R. Ihre, Omayra L. Padilla De Jesus, Francis C. Szoka, Jean M. J. Frechet
https://www.ncbi.nlm.nih.gov/pubmed/12009933
We evaluated various dendritic architectures composed of a polyester dendritic scaffold based on the monomer unit 2,2-bis(hydroxymethyl)propanoic acid for their suitability as drug carriers both in vitro and in vivo. These systems are both water soluble and nontoxic.Author: Omayra L. Padilla De Jesus, Henrik R. Ihre, Lucie Gagne, Jean M. J. Frechet, Francis C. Szoka
https://freepaper.me/downloads/abstract/10.1021/bc010102u
Polyester Dendritic Systems for Drug Delivery Applications: Design, Synthesis, and Characterization Attachment of drugs to high molecular weight polymers can significantly improve both tumor targeting and therapeutic efficacy due to the enhanced permeability and retention effect observed in tumor tissue.
https://www.researchgate.net/publication/11361373_Polyester_Dendritic_Systems_for_Drug_Delivery_Applications_In_Vitro_and_In_Vivo_Evaluation
Request PDF Polyester Dendritic Systems for Drug Delivery Applications: In Vitro and In Vivo Evaluation High molecular weight polymers (> 20 000 Da) have been widely used as soluble drug ...
https://www.researchgate.net/publication/11361372_Polyester_Dendritic_Systems_for_Drug_Delivery_Applications_Design_Synthesis_and_Characterization
Request PDF Polyester Dendritic Systems for Drug Delivery Applications: Design, Synthesis, and Characterization Attachment of drugs to high molecular weight polymers can significantly improve ...
https://www.mdpi.com/2073-4360/6/1/179/pdf
drug delivery systems based on block copolymer micelles or dendritic systems have shown great promise and utility for tumor targeting and drug delivery [8,19,99–103]. Both covalent and non-covalent systems can utilize the enhanced permeability and retention (EPR) phenomenon [9–11].Author: Amour K. Twibanire, T. Bruce Grindley
https://www.sigmaaldrich.com/materials-science/learning-center/technology-spotlights/dendritic-polyester-scaffolds.html
The dendritic family of bis-MPA scaffolds has proven to be an efficient tool for delivery of both physically and covalently attached drugs. The preparation of drug unimolecular carriers based on bis-MPA polyester scaffolds is described herein.
https://www.sciencedirect.com/science/article/pii/S1359644604032763
Fréchet and colleagues [23, 24] have also recently explored polyester dendrimers based on the monomer 2,2-bis(hydroxymethyl)propionic acid and their hybrids with PEO as candidates for the development of anticancer drug delivery systems. Various polyester dendrimers incorporating monomers such as glycerol, succinic acid, phenylalanine and lactic acid have been prepared by Grinstaff et al., and …Author: Elizabeth R. Gillies, Jean M.J. Fréchet
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