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https://www.rnspeak.com/polio-vaccines/
Recently, the Philippine Department of Health issued a health advisory intended for people traveling to areas such as the Philippines which had the reemergence of cases of polio. It has declared polio epidemic thus measures of pre-vaccination are advised. According to the DOH, those traveling to the Philippines must receive a single dose of inactivated poliovirus vaccine.
https://www.cincinnati.com/story/news/2019/05/10/our-history-albert-sabin-jonas-salk-competed-for-safest-polio-vaccine/1140590001/
May 10, 2019 · Our history: Sabin and Salk competed for safest polio vaccine. The quest to develop an effective polio vaccine was a competition, yet both the Salk vaccine and the …Author: Jeff Suess
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132247/
May 15, 2017 · 2. Oral administration. Oral delivery is the most desirable and patient-accepted route of administration, with over 60% of commercialized small molecule drug products using the oral route [23,24].Despite this, only a small fraction of currently licensed vaccines are oral formulations due to the inherent obstacles presented by the gastrointestinal system.Author: Julia E. Vela Ramirez, Lindsey A. Sharpe, Nicholas A. Peppas
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514067/
The TRG delivery system group also displayed the strongest mucosal IgA antibody titers in salivary and fecal samples, with highest responses against IPV1 and IPV3 (Fig. 2). SL immunization with vaccine formulated in DPBS (without TRG or adjuvant) elicited minimal to no response for any IPV serotype (Figs. 2 …Author: Jessica A White, Jeremy S Blum, Nancy A Hosken, Joshua O Marshak, Lauren Duncan, Changcheng Zhu, Eli...
https://www.historyofvaccines.org/timeline/polio
For a time, polio was called infantile paralysis, though it did not affect only the young. Cause of Polio. Polio is caused by one of three types of poliovirus (which are members of the Enterovirus genus). These viruses spread through contact between people, by nasal and oral secretions, and by contact with contaminated feces.
https://www.who.int/bulletin/volumes/87/12/08-061556/en/
Providing monovalent oral polio vaccine type 1 to newborns: findings from a pilot birth-dose project in Moradabad district, India JJ Rainey a, P Bhatnagar b, CF Estivariz a, S Durrani b, M Galway c, H Sandhu a, S Bahl b, H Jafari a & J Wenger b. a. US Centers for Disease Control and Prevention, Global Immunization Division,1600 Clifton Road (MS E-05), Atlanta, GA, 30333, United States of America.
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