We have collected information about Plga Sirna Delivery for you. Follow the links to find out details on Plga Sirna Delivery.
https://www.sciencedirect.com/science/article/pii/S016836591001000X
The cationic siRNA–PLGA/LPEI micelles showed superior intracellular uptake and enhanced gene silencing effect, compared to naked siRNA/LPEI complexes. The hybrid micelle structure based on siRNA and PLGA can be potentially used as an efficient siRNA delivery system for gene silencing.Author: Soo Hyeon Lee, Hyejung Mok, Yuhan Lee, Tae Gwan Park
https://www.nature.com/articles/s41598-018-25930-7
May 14, 2018 · Herein, we synthesized PLGA nanoparticles (PLGA NPs) as a co-delivery nanocarrier for MDR1 and BCL2 siRNA by using poly-L-lysine (PPL) as a complexing reagent, and demonstrated that siRNA …Author: Chitra Risnayanti, Chitra Risnayanti, Yeong-Su Jang, Jinju Lee, Hyung Jun Ahn
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2660441/
Feb 09, 2009 · Gene silencing using small interfering RNA (siRNA) has several potential therapeutic applications. In the present study, we investigated nanoparticles formulated using the biodegradable polymer, poly(d, l-lactide-co-glycolide) (PLGA) for siRNA delivery.A cationic polymer, polyethylenimine (PEI), was incorporated in the PLGA matrix to improve siRNA encapsulation in PLGA nanoparticles.Author: Yogesh Patil, Yogesh Patil, Jayanth Panyam
https://www.nature.com/articles/s41598-019-52142-4
Nov 01, 2019 · Short interfering RNA (siRNA) possesses special ability of silencing specific gene. To increase siRNA stability, transportation and its uptake by tumor cells, effective delivery to the appropriate ...Author: Azmat Ali Khan, Amer M. Alanazi, Mumtaz Jabeen, Arun Chauhan, Mohammad Azam Ansari
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3211866/
Jul 12, 2011 · To enhance gene delivery effect, various cationic complexes have been developed for delivering plasmid DNA, antisense, or siRNA into cells [7-9]. Poly(D, L-lactide-co-glycolide) (PLGA) were extensively assessed for their ability of delivering variety of therapeutic agents [10-12].Author: Gao Feng Liang, Yan Liang Zhu, Bo Sun, Fei Hu Hu, Tian Tian, Shu Chun Li, Zhong Dang Xiao
https://pubs.acs.org/doi/10.1021/nn300106t
Composite nanofibers of biodegradable poly(d,l-lactic-co-glycolic acid) (PLGA) encapsulating chitosan/siRNA nanoparticles (NPs) were prepared by electrospinning. Acidic/alkaline hydrolysis and a bulk/surface degradation mechanism were investigated in order to achieve an optimized release profile for prolonged and efficient gene silencing.Author: Menglin Chen, Shan Gao, Mingdong Dong, Jie Song, Chuanxu Yang, Kenneth Alan Howard, Jørgen Kjems, Fl...
https://www.sciencedirect.com/science/article/pii/S0142961211011379
We have developed PLGA-based nanoparticles that provide targeted and efficient delivery of siRNA. These nanoparticles are truly multifunctional and offer several advantages over other technologies for siRNA delivery. First, PLGA, the major biomaterial used in this nanoparticle synthesis, has been safely used in clinical applications for many ...Author: Jiangbing Zhou, Toral R. Patel, Michael Fu, James P. Bertram, W. Mark Saltzman
http://pubs.acs.org/doi/abs/10.1021/nl2035354
The PRINT process enables high encapsulation efficiency of siRNA into neutral and monodisperse PLGA particles (32–46% encapsulation efficiency). Lipid-coated PLGA/siRNA PRINT particles were used to deliver therapeutic siRNA in vitro to knockdown genes relevant to prostate cancer.
https://cancerres.aacrjournals.org/content/78/21/6247
Nov 01, 2018 · In vivo selective delivery of HA-PLGA (PTX+siRNA)-NPs in a mouse model. Receptor-targeted delivery of the NPs was assessed as previously described . CD44-positive, HeyA8-bearing mice were given a single injection of either nontargeted PLGA (PTX+siRNA)-NPs or targeted HA-PLGA (PTX+siRNA)-NPs, both labeled with FITC.Author: Yeongseon Byeon, Jeong Won Lee, Whan Soo Choi, Ji Eun Won, Ga Hee Kim, Min Gi Kim, Tae In Wi, Jae My...
https://www.mdpi.com/1422-0067/13/1/516/pdf
by the combination of mPEG-PLGA-PLL with siRNA, a gel retardation assay was performed in this study. As shown in Figure 4, complete binding of siRNA with the mPEG-PLGA-PLL (without the presence of a free siRNA band) could be observed when the weight ratio of the triblock copolymer/siRNAAuthor: Jing Du, Ying Sun, Qiu-Sheng Shi, Pei-Feng Liu, Ming-Jie Zhu, Chun-Hui Wang, Lian-Fang Du, You-Rong ...
Searching for Plga Sirna Delivery?
You can just click the links above. The data is collected for you.
