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https://www.sigmaaldrich.com/technical-documents/articles/technology-spotlights/degradex-microspheres-nanoparticles.html
Plain PLGA microspheres and nanoparticles can be used in drug delivery research and formulation as control agents or can be used to test system compatibility before loading an API into the carrier. Fluorescent nanoparticles and microspheres can be used in imaging and diagnostic applications for the detection of binding events or signal enhancement.
https://www.sigmaaldrich.com/materials-science/material-science-products.html?TablePage=119957384
Poly (lactic-co-glycolic acid) (PLGA) particles often serve as a biodegradable and biocompatible platform for drug delivery 1. We offer Degradex ® PLGA microspheres and nanoparticles from 100 nm to 50 μm in diameter, which are adaptable to a wide array of applications from drug delivery...
https://www.sciencedirect.com/science/article/pii/S131901641400111X
PLGA-mesalamine microspheres provides the controlled drug delivery as compared to suspension of the same drug, which shows effective targeted drug delivery to inflamed site in ulcerative colitis: Mahajan et al. (2011) 8. Naproxen sodium using sodium alginate and Eudragit S100 as mucoadhesive and pH-sensitive polymer: Eudragit S-100 and sodium ...Author: Nidhi, Muzamil Rashid, Veerpal Kaur, Supandeep Singh Hallan, Saurabh Sharma, Neeraj Mishra
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518665/
Jan 10, 2013 · PLGA is a bulk-eroding polymer at the length scales used in drug delivery microspheres (10s to 100s of microns) as the hydration time scale is on the order of a few minutes compared to weeks or months for degradation [24-26].Author: Ashlee N. Ford Versypt, Ashlee N. Ford Versypt, Daniel W. Pack, Daniel W. Pack, Richard D. Braatz, R...
https://link.springer.com/chapter/10.1007%2F978-0-387-25842-3_2
Thus, there is a corresponding need for safer and more effective methods and devices for drug delivery. Indeed, drug delivery systems—designed to provide a therapeutic agent in the needed amount, at the right time, to the proper location in the body, in a manner that optimizes efficacy, increases compliance and minimizes side effects—were ...Author: Kyekyoon Kevin Kim, Daniel W. Pack
http://microspheres.us/microparticles/plga
Chitosan Coated PLGA-Microspheres – A Modular System for Targeted Drug Delivery During some research on PLGA microspheres we found this interesting article published in European Cells and Materials Vol 7 Suppl 2. 2004 (pages 11-12) .
https://www.ncbi.nlm.nih.gov/pubmed/14680467
Polymeric microspheres are ideal vehicles for many controlled delivery applications due to their ability to encapsulate a variety of drugs, biocompatibility, high bioavailability and sustained drug release …Author: Neelesh K Varde, Daniel W Pack
https://www.jgtps.com/admin/uploads/YqxI0h.pdf
Microspheres for oral use have been employed to sustain the drug release, and to reduce or eliminate gastrointestinal tract irritation. In addition, multiparticulate delivery systems spread out more uniformly in the gastrointestinal tract. This results in more reproducible drug absorption and reduces localFile Size: 1MB
https://www.researchgate.net/publication/270765946_PLGA_A_unique_polymer_for_drug_delivery
PLGA: A unique polymer for drug delivery. ... A wide range of PLGA-based drug delivery systems have been reported for the treatment or diagnosis of various diseases and disorders. ... microspheres ...
http://www.degradex.com/about-degradexreg-products.html
Degradex® PLGA microspheres are polymeric particles in the size range of microns to millimeters. PLGA polymers have been used to encapsulate drug molecules. Drug loaded PLGA microspheres are used as long-acting, sustained release pharmaceutical formulations.
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