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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347861/
Sep 01, 2011 · In past two decades poly lactic-co-glycolic acid (PLGA) has been among the most attractive polymeric candidates used to fabricate devices for drug delivery and tissue engineering applications.PLGA is biocompatible and biodegradable, exhibits a wide range of erosion times, has tunable mechanical properties and most importantly, is a FDA approved polymer.Author: Hirenkumar K. Makadia, Steven J. Siegel
https://www.sigmaaldrich.com/technical-documents/articles/technology-spotlights/degradex-microspheres-nanoparticles.html
Degradex ® PLGA Particles. Degradex ® PLGA microspheres and nanoparticles are polymeric particles in the size range of nanometers to microns. Both plain and fluorescently dyed particles are available. Plain PLGA microspheres and nanoparticles can be used in drug delivery research and formulation as control agents or can be used to test system compatibility before loading an API into the carrier.
https://www.jgtps.com/admin/uploads/YqxI0h.pdf
targeting of drugs. In future microspheres will find the central place in novel drug delivery, particularly in diseased cell sorting, diagnostics, genetic materials, targeted and effective drug delivery. The current aim of this review is to study various aspects of the microparticulates drug delivery system including method ofFile Size: 1MB
https://www.sciencedirect.com/science/article/pii/S0169409X12002645
Biodegradation and biocompatibility of PLA and PLGA ... The sequence of events following implantation of a microsphere drug delivery system is illustrated in Fig. 3 and Table 2 ... nanospheres have been included as a subsection and significant issues dealing with the biodegradation and biocompatibility of nanospheres are included in the review. ...Author: James M Anderson, Matthew S Shive
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518665/
Jan 10, 2013 · PLGA microspheres are widely studied for controlled release drug delivery applications, and many models have been proposed to describe PLGA degradation and erosion and drug release from the bulk polymer. Autocatalysis is known to have a complex role in ...Author: Ashlee N. Ford Versypt, Ashlee N. Ford Versypt, Daniel W. Pack, Daniel W. Pack, Richard D. Braatz, R...
http://www.degradex.com/degradexreg-plga-microspheres.html
24 rows · We offer a full range of Degradex ® PLGA microspheres and PLGA nanoparticles that are …
https://www.sciencedirect.com/science/article/pii/S0142961203004137
Among the various biodegradable polyesters, PLGA [poly(d, l-lactide-co-glycolide)] was particularly suitable to be used for the drug delivery application. PLGA polymers are already approved by the US Food and Drug Administration (FDA), such as biodegradable structures, implantable screws, pins, drug delivery devices and tissue engineering ...Author: Fwu Long Mi, Shin Shing Shyu, Yi Mei Lin, Yu Bey Wu, Chih Kang Peng, Yi Hung Tsai
https://www.pharmamanufacturing.com/articles/2018/the-art-of-the-science/
Aug 21, 2018 · Scientific and technologic discovery is a critical driver for improving clinical care. Flexion’s experience with Zilretta underscores how critical drug delivery innovation is, and highlights how continued advances in the development of novel PLGA microsphere formulations …
http://www.americanpharmaceuticalreview.com/Featured-Articles/188841-FDA-s-Regulatory-Science-Program-for-Generic-PLA-PLGA-Based-Drug-Products/
Jun 15, 2016 · Polylactide (PLA)/Poly(lactide-co-glycolide) (PLGA) is widely used in many FDA-approved drug products. There are currently 15 FDA-approved PLA/PLGA-based drug products available on the US market (Table 1). PLA/PLGA-based drug products are designed to reduce dosing frequency and potential drug toxicity. They are also useful for improving patient compliance with a better therapeutic …
https://www.researchgate.net/publication/266761665_PLGA_Microspheres_Containing_Minocycline_as_Drug_Delivery_System
Among different forms of PLGA-based drug delivery systems, microspheres or microparticles are the most common. Methods: The microspheres containing Minocycline were prepared by the w/o/w double ...
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