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https://cvphysiology.com/CAD/CAD002
Therefore, the oxygen delivery to the heart under resting conditions is about 16 ml O 2 /min per 100g. The maximal concentration of oxygen in the arterial blood is primarily determined by the oxygen that is bound to hemoglobin in the red blood cells (erythrocytes). Only a …
https://cvphysiology.com/CAD/CAD003
The additional increase in MVO 2 above this basal level is that required to support myocyte contraction and relaxation. In order to support MVO 2, particularly during times of increased oxygen demand (e.g., during exercise), the heart must extract oxygen from the arterial blood supplying the myocardium (see Oxygen Supply).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391739/
Increased catecholamines increase myocardial oxygen delivery, myocardial oxygen consumption and cause focal degeneration of the myocardium, and hypertrophy. In excess, they cause cardiac deficiency, local myocardial hypoxia, and cardiac death. 27 Thus, prolonged exposure to catecholamine levels 10-fold higher than normal is cause for clinical ...
https://www.physiology.org/doi/full/10.1152/ajpheart.00321.2017
Oxygen-carrying perfluorocarbons increase myocardial oxygen delivery and improve cardiac function, providing a more physiological mitochondrial redox state and emphasizing cardiac work is modulated by myocardial oxygen delivery. ... Hemoglobin or erythrocytes, however, interfere with optical assessments of myocardial physiology, a critical ...Author: Sarah Kuzmiak-Glancy, Raúl Covian, Armel N. Femnou, Brian Glancy, Rafael Jaimes, Anastasia M. Wengro...
https://www.sciencedirect.com/topics/medicine-and-dentistry/heart-muscle-oxygen-consumption
An increase in myocardial oxygen demand, caused by an increase in wall tension, contractility, or heart rate, requires an increase in oxygen supply or else results in myocardial ischemia. Because myocardial oxygen extraction from blood is already near maximal, the only mechanism to satisfy an increase in oxygen demand is to increase blood flow ...
https://quizlet.com/215132250/chapter-6-exercise-physiology-flash-cards/
Start studying Chapter 6 Exercise Physiology. Learn vocabulary, terms, and more with flashcards, games, and other study tools. ... (working myocardial cells) gap junctions. intercalated discs ... -increase oxygen delivery to muscle
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1114207/
Nov 07, 1998 · Physiology of oxygen transport. Although oxygen is the substrate that cells use in the greatest quantity and on which aerobic metabolism and cell integrity depend, the tissues have no storage system for oxygen. They rely on a continuous supply at a …Author: D F Treacher, R M Leach
http://www.partone.lifeinthefastlane.com/myocardial_oxygen_supply_and_demand.html
Myocardial Oxygen Supply and Demand. Describe myocardial oxygen demand and supply, and the conditions that may alter each. Myocardial oxygen supply is a function of coronary blood flow; Myocardial oxygen demand is determined by myocardial work; Myocardial ischaemia occurs when demand exceeds supply; Myocardial Oxygen Supply
https://journals.physiology.org/doi/full/10.1152/japplphysiol.01345.2003
Powerful mechanisms increase coronary blood flow whenever myocardial oxygen consumption is increased. Without these mechanisms, decreased cardiac output, hypotension, arrhythmias, and death would result. The purpose of the present paper is to review the mechanisms that match oxygen delivery to myocardial oxygen consumption via coronary blood flow.Author: Johnathan D. Tune, Mark W. Gorman, Eric O. Feigl
https://cvpharmacology.com/Angina/antianginal
Angina results from a reduction in the oxygen supply/demand ratio. Therefore, in order to alleviate the pain, it is necessary to improve this ratio. This can be done either by increasing blood flow (which increases oxygen delivery or supply), or by decreasing oxygen demand (i.e., by decreasing myocardial oxygen consumption).
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