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https://www.ncbi.nlm.nih.gov/pubmed/379050
Periodontal therapy by local delivery of tetracycline. The present investigation assessed the feasibility of treating periodontal disease by controlled delivery of antibacterial agents from within periodontal pockets.Author: J. M. Goodson, A. Haffajee, S. S. Socransky
https://onlinelibrary.wiley.com/doi/10.1111/j.1600-051X.1979.tb02186.x
Skip to Article Content; Skip to Article InformationAuthor: J. M. Goodson, A. Haffajee, S. S. Socransky
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921381/
Local drug delivery with tetracycline fibers has also a role to play in the treatment of peri-implantitis sites as observed in microbiological studies . To conclude scaling and root planing is an extremely effective treatment modality for controlling early to moderate periodontitis.Author: M Panwar, SH Gupta
http://onlinelibrary.wiley.com/doi/10.1111/j.1600-051X.1979.tb02186.x/abstract
Dec 14, 2005 · The present investigation assessed the feasibility of treating periodontal disease by controlled delivery of antibacterial agents from within periodontal pockets. Tetra-cycline-filled hollow fibers placed in the gingival sulcus were shown to have a dramatic effect both on the periodontal microflora and clinical manifestations of disease.
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1600-051X.1979.tb02186.x
The present investigation assessed the feasibility of treating periodontal disease by controlled delivery of antibacterial agents from within periodontal pockets. Tetra‐cycline‐filled hollow fibers placed in the gingival sulcus were shown to have a dramatic effect both on the periodontal microflora and clinical manifestations of disease.Author: J. M. Goodson, A. Haffajee, S. S. Socransky
https://www.sciencedirect.com/science/article/pii/S0377123709800142
Local drug delivery with tetracycline fiber is an effective and simple non surgical method to improve periodontal health which can be practiced even by a general dental practitioner. Previous article in issue Next article in issueAuthor: M Panwar, SH Gupta
https://www.ncbi.nlm.nih.gov/pubmed/3891959/
Periodontal disease treatment by local drug delivery. Goodson JM, Offenbacher S, Farr DH, Hogan PE. The subgingival microbiologic composition of diseased periodontal sites was evaluated by darkfield microscopy before and after scaling or local delivery of tetracycline. A standardized sampling and counting method using a crevicular washing...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963762/
As a local drug delivery system, tetracycline is used widely in periodontal treatment as it is active against periodonto-pathogenic microorganism [5,6]. It possesses widespread bacteriostatic properties and acts slowly by binding to the tooth surface, inhibiting the activity of collagenase at low concentrations and thus preventing periodontal tissue destruction [ 7 , 8 ].Author: Sara Abbas, Jaideep Mahendra, Geetha Ari
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209612/
So, from this clinical study, it can be suggested that controlled local drug delivery system using Periodontal Plus AB (tetracycline fiber) is a simple, rapid, and non-invasive procedure. So, this can be a good treatment modality to reduce probing pocket depth, along with providing more favorable clinical attachment gain in chronic generalized periodontitis.
https://www.researchgate.net/publication/327499589_Local_drug_delivery_in_periodontal_diseases-_A_review
Local delivery of antimicrobials has been investigated for the possibility of overcoming the limitations of conventional therapy. The use of sustained release formulations to deliver antibacterials to the site of infection (periodontal pocket) has recently gained interest.
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