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https://www.ncbi.nlm.nih.gov/pubmed/16243265
Nov 01, 2005 · 1. Drug Discov Today. 2005 Nov 1;10(21):1451-8. PEGylation, successful approach to drug delivery. Veronese FM(1), Pasut G. Author information: (1)Department of Pharmaceutical Sciences, Padua University, Italy. [email protected] PEGylation defines the modification of a protein, peptide or non-peptide molecule by the linking of one or more polyethylene glycol (PEG) chains.Author: Francesco M. Veronese, Gianfranco Pasut
https://www.sciencedirect.com/science/article/pii/S1359644605035750
The PEG-drug conjugates have several advantages: a prolonged residence in body, a decreased degradation by metabolic enzymes and a reduction or elimination of protein immunogenicity. Thanks to these favorable properties, PEGylation now plays an important role in drug delivery, enhancing the potentials of peptides and proteins as therapeutic agents.Author: Francesco M. Veronese, Gianfranco Pasut
http://laysanbio.com/clientuploads/Veronese-Pegylation-Drug-Discovery-Today-2005-10-1451-1458.pdf
PEGylation,successful approach to drug delivery Francesco M.Veronese and Gianfranco Pasut PEGylation defines the modification of a protein, peptide or non-peptide molecule by the linking of one or more polyethylene glycol (PEG) chains. This polymer is non-toxic, non-immunogenic, non-antigenic, highly soluble in water and FDA approved.
https://www.researchgate.net/publication/311534729_PEGylation_successful_approach_to_drug_delivery
Request PDF On Jan 1, 2008, F.M. Veronese and others published PEGylation, successful approach to drug delivery Find, read and cite all the research you need on ResearchGate
https://www.academia.edu/13685548/PEGylation_successful_approach_to_drug_delivery
PEGylation, successful approach to drug delivery
https://www.semanticscholar.org/paper/PEGylation%2C-successful-approach-to-drug-delivery.-Veronese-Pasut/0dcda728b619919ec6de88f47c816ca8f4a30c58
PEGylation, successful approach to drug delivery. @article{Veronese2005PEGylationSA, title={PEGylation, successful approach to drug delivery.}, author={Francesco Maria Veronese and Gianfranco Pasut}, journal={Drug discovery today}, year={2005}, volume={10 21}, pages={ 1451-8 } } Francesco Maria Veronese, Gianfranco Pasut
https://www.powershow.com/viewfl/44883a-Yzk4Z/PEGylation_A_successful_Approach_to_Drug_Delivery_powerpoint_ppt_presentation
PEGylation, successful approach to drug delivery. Drug Discovery Today. 2005 Nov 10(21) Veronese M. and Pasut G. 3 Current Drug Problems Diagram transpeg.pbwiki.com 4 PEG - Polyethylene Glycol. Synthesized from the polymerization of ethylene oxide ; Using chemical tools to link PEG molecules to native proteins can yield conjugates with more
https://www.sciencedirect.com/science/article/pii/S0168365914004556
A number of PEGylating agents are available in the market which range from monofunctional to homo-/hetero-bifunctional PEG products. Therefore, this review focuses on the role of PEGylation in drug delivery with emphasis on understanding the chemistry of substrate and the PEGylating agents and conditions used for conjugation.Author: Atul Kolate, Dipesh Baradia, Sushilkumar Patil, Imran Vhora, Girish Kore, Ambikanandan Misra
https://www.researchgate.net/publication/7523824_Veronese_FM_Pasut_G_PEGylation_successful_approach_to_drug_delivery_Drug_Discov_Today_10_1451-1458
Veronese, F.M. & Pasut, G. PEGylation, successful approach to drug delivery. Drug Discov. Today 10, 1451-1458
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624571/
With numerous PEGylated drugs approved by the Food and Drug Administration (FDA) to treat a variety of diseases and many more in clinical and pre-clinical development , PEGylation has become the most widely used approach to effectively improve the stability, solubility and pharmacokinetics and to reduce the immunogenicity of protein/peptide ...Author: Yizhi Qi, Ashutosh Chilkoti
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