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https://onlinelibrary.wiley.com/doi/full/10.1111/jphp.13098
Nuclear targeting. Beside the drug delivery to the TME or more precisely to the tumour cells, some treatments need an even more precise level which is the drug delivery at organelle level, for example, nucleus, lysosomes, mitochondria or endoplasmic reticulum. ... A combination of active or passive drug carrier with an imaging or a diagnostic ...Author: Mohamed F. Attia, Mohamed F. Attia, Nicolas Anton, Justine Wallyn, Ziad Omran, Thierry F. Vandamme
https://link.springer.com/chapter/10.1007%2F978-3-642-00477-3_1
Nov 19, 2009 · Among various approaches to specifically target drug-loaded carrier systems to required pathological sites in the body, two seem to be most advanced – passive (EPR effect-mediated) targeting, based on the longevity of the pharmaceutical carrier in the blood and its accumulation in pathological sites with compromised vasculature, and active ...Author: Vladimir P. Torchilin
https://www.medscape.com/viewarticle/770397_3
Nov 06, 2019 · Targeting Strategies . Two basic requirements should be realized in the design of nanocarriers to achieve effective drug delivery (Figure 2). First, drugs should be able to …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4179822/
Jul 23, 2014 · There are two ways by which targeting of nanoparticles may be achieved, namely passive and active targeting. The aim of this study was to provide a comprehensive review of the literature focusing on passive targeting. ... Passive and active drug targeting: drug delivery to tumors as an example. Handb Exp Pharmacol. 2010; 197:3–53.Author: Remon Bazak, Mohamad Houri, Samar El Achy, Wael Hussein, Tamer Refaat
https://www.researchgate.net/publication/41850483_Passive_and_Active_Drug_Targeting_Drug_Delivery_to_Tumors_as_an_Example
There are two strategies for active and passive targeting in the design of drug delivery systems. In passive targeting, anatomical discrepancies between the normal tissue and the overtaken tissue ...
https://www.medscape.com/viewarticle/752329_6
Oct 18, 2019 · Passive & Active Targeting of Liposomes as Drug Delivery Systems for the Treatment of TB Liposomes can be targeted to specific organs or tissues by passive and active methods (Figure 5).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219254/
Active targeting increases the affinity of the NPs for tumor cells, increasing its tumor residence times and allowing the drug-loaded NPs to efficiently enter the cells through receptor mediated endocytosis. The principles and future development of active targeting using affinity ligands on the surface of NPs will be presented in the next section.Author: Nicolas Bertrand, Jun Wu, Xiaoyang Xu, Xiaoyang Xu, Nazila Kamaly, Omid Cameron Farokhzad
https://www.hindawi.com/journals/jnm/2016/1087250/
In this paper, we provide an overview of three different targeted drug delivery methods (passive targeting, active targeting, and physical targeting) and compare methods of action, advantages, limitations, and the current stages of research. For the most commonly used …Author: Xiaojiao Yu, Ian Trase, Muqing Ren, Kayla Duval, Xing Guo, Zi Chen
https://link.springer.com/chapter/10.1007%2F978-3-319-08084-0_1
Sep 06, 2014 · Delivery of nanocarriers is achieved either via “passive targeting” owing to the enhanced permeability and retention (EPR) effect or via “active targeting” due to the presence of various ligands on the surface of nanocarriers, such as antibodies, peptides, etc. Numerous factors are involved in successful delivery of chemotherapeutic ...Author: Jaydev R. Upponi, Vladimir P. Torchilin
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