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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806207/
Feb 18, 2013 · The encapsulation of paclitaxel in biodegradable and non-toxic nano-delivery systems can protect the drug from degradation during circulation and in-turn protect the body from toxic side effects of the drug thereby lowering its toxicity, increasing its circulation half-life, exhibiting improved pharmacokinetic profiles, and demonstrating better patient compliance.Author: Ping Ma, Russell J. Mumper
https://www.researchgate.net/publication/234068190_Paclitaxel_drug_delivery_systems
Paclitaxel drug delivery systems. Introduction: Paclitaxel (PTX) is one of the most effective broad-spectrum chemotherapeutic agents in the treatment of cancers. However, its clinical application has been limited due to its poor water solubility.
https://www.sigmaaldrich.com/catalog/papers/23289542
Paclitaxel drug delivery systems. Paclitaxel (PTX) is one of the most effective broad-spectrum chemotherapeutic agents in the treatment of cancers. However, its clinical application has been limited due to its poor water solubility.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425796/
Aug 12, 2012 · Among alternative experimental delivery systems of paclitaxel, nanoparticles of various biodegradable polymers and bioadhesive materials have been considered as promising. Nanotechnology can help to improve the bioavailability of poorly soluble drugs such as paclitaxel, enhancing drug delivery . Nanoparticles also have the ability to permeate through certain tissues, …Author: Madhu S. Surapaneni, Sudip K. Das, Nandita G. Das
https://www.tandfonline.com/doi/abs/10.1517/17425247.2013.752354
Sep 04, 2014 · Expert opinion: Pharmaceutical nanotechnology can provide solutions to solve the problems encountered in drug formulation and drug delivery and may change the way drugs are made. The various nanocarriers could have high efficiency in drug encapsulation and cellular uptake, escape from elimination by microphages due to their appropriate size and surface modification and realize with ligand conjugation-targeted delivery.Author: Zhiping Zhang, Lin Mei, Si-Shen Feng
https://www.sciencedirect.com/science/article/pii/S0001868618302021
Again, it is seen that co-administration of paclitaxel and C 6 -ceramide in nanoemulsions as delivery systems leads to an augmentation in apoptotic activity. For instance, the apoptotic activity in the presence of 100 nM paclitaxel increased from 12% (in aqueous solution) to 67% (in nanoemulsion) [ 50 ].Author: S. Ezrahi, A. Aserin, N. Garti
http://www.eurekaselect.com/122660/article
Keywords:Cancer, drug delivery systems, liposomes, nanoparticles, paclitaxel. Abstract:Paclitaxel (PTX), a taxane plant product, is one of the most effective broad-spectrum anti-cancer agents and approved for the treatment of a variety of cancers including ovarian, …
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