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https://www.miltenyibiotec.com/US-en/products/macs-cell-culture-and-stimulation/stimulation-reagents/antigens-and-peptide-pools/ova-antigen-delivery-module-set.html
The Ova Antigen Delivery Reagent has been developed for efficient in vitro targeting of ovalbumin to antigen-presenting cells (APCs), for example, DCs. The reagent consists of a monoclonal anti-biotin antibody conjugated to ovalbumin and FITC.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774884/
Aug 03, 2009 · The observation that α 2 M*-mediated antigen delivery is capable of enhancing specific CTL responses provides new support for the use of α 2 M* as an in vivo antigen-delivery vehicle. Although originally thought to promote only MHC class II presentation [ 18 ], it now appears evident that α 2 M*-mediated antigen delivery also promotes the cross-presentation of exogenous antigen onto …Author: Edith V. Bowers, Jeffrey J. Horvath, Jennifer E. Bond, George J. Cianciolo, Salvatore V. Pizzo
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338492/
Jan 17, 2019 · Given the robustness of CD169MØ targeting in vivo, we next investigated if a protein antigen, ovalbumin (OVA), could be selectively delivered to CD169MØs for activation of OVA specific CD4 + (OT-II) or CD8+ (OT-I) T cells.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650639/
Ovalbumin (OVA) was used as the model antigen to study the efficiency of YS in delivering antigen. By incubation with NaIO 4 -oxidized YS, OVA was chemically linked to the surface of YS, forming YS-OVA particles with a drug load of 20%.Author: Ying Pan, Xiaopeng Li, Tianyi Kang, Hui Meng, Zhouli Chen, Li Yang, Yang Wu, Yuquan Wei, Maling Gou
https://www.sciencedirect.com/science/article/pii/S2451945618303398
By adapting the platform to delivery of a TLR7 agonist, we demonstrated that CD169MØs can be classically activated in a manner similar to other macrophage subsets, and that this activation presented a pathway for expansion of antigen-specific CD8 + T cells through delivery of liposome-encapsulated antigen.Author: Landon J. Edgar, Norihito Kawasaki, Corwin M. Nycholat, James C. Paulson
https://www.sigmaaldrich.com/catalog/papers/24682172
Using a minimized aptamer conjugated to the model antigen ovalbumin (OVA), DEC205-targeted antigen crosspresentation was verified in vitro and in vivo by proliferation and cytokine production by primary murine CD8 (+) T cells expressing a T cell receptor specific for …
https://www.miltenyibiotec.com/GB-en/products/macs-cell-culture-and-stimulation/stimulation-reagents/antigens-and-peptide-pools/hcmv-pp65-antigen-delivery-reagent.html
The hCMV-pp65 Antigen Delivery Reagent has been developed for specific targeting of pp65 CMV antigen to antigen uptake receptors on human APCs. Such targeted delivery of antigen allows the analysis of antigen uptake, processing, and antigen presenting capability of targeted APCs.
https://www.taconic.com/find-your-model/gems/cryopreserved-models/knockout-repository/phenotypic-data-packages/comprehensive/ovalbumin-challenge.html
Immunology: Ovalbumin (OVA) Challenge Chicken OVA is a T Cell-dependent antigen commonly used as a model protein for studying antigen-specific immune responses in mice. It is non-toxic and inert and therefore will not cause harm to the animals even if no immune response is induced.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599097/
Aug 18, 2017 · A variety of factors influence the strength and quality of the CTL response, including the nature of the DC subset, the duration of antigen presentation, and the type of costimulatory signals received by the naive CD8 + T cells. 1,3 The BDCA3 + DC subset (in humans) and the CD8α + DC subset (in the mouse) excel in antigen cross-presentation and the priming of CD8 + T cells. 4-6 …Author: Reem Ghinnagow, Julie De Meester, Luis Javier Cruz, Caroline Aspord, Stéphanie Corgnac, Elodie Macho...
https://www.researchgate.net/post/Why_is_chichen_ovalbumin_chosen_as_one_of_the_most_popular_model_antigen2
Another reason for the current popularity of OVA as a model antigen are research tools such as OT-1 and OT-II OVA-specific TCR transgenic mice and monoclonal antibodies such as 25D.1 that bind to ...
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