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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407637/
Jul 17, 2012 · 5.7. Liquid-Oral Osmotic (L-OROS) System. Various L-OROS systems available to provide controlled delivery of liquid drug formulations include L-OROS hardcap, L-OROS softcap, and a delayed liquid bolus delivery system. Each of these systems includes a liquid drug layer, an osmotic engine or push layer, and a semipermeable membrane coating.Author: Rajesh A. Keraliya, Chirag Patel, Pranav Patel, Vipul Keraliya, Tejal G. Soni, Rajnikant C. Patel, M...
http://www.thepharmajournal.com/vol1Issue7/Issue_sept_2012/23.1.pdf
The osmotic-controlled release oral delivery system, OROS, is an advanced drug delivery technology that uses osmotic pressure as the driving force to deliver pharmacotherapy, usually once-daily, in several therapeutic areas.
https://openi.nlm.nih.gov/detailedresult.php?img=PMC2656329_ndt-3-869f1&req=4
The osmotic push–pull tablet: cross-section of bilayer tablet before and after ingestion. Reprinted with permission from Conley R, Gupta SK, Sathyan G. 2006. Clinical spectrum of the osmotic-controlled release oral delivery system (OROS®), an advanced oral delivery form.
http://ijpacr.com/files/05-5.pdf
Fig. 2: Schematic diagram of Push pull Osmotic Pump OROS CT System The OROS-CT TM system was designed for colon-targeted drug delivery. The system might contain as many as push-pull units enclosed within a hard gelatin capsule, immediately after ingestion the hard gelatin capsule shell dissolves. However, the pushFile Size: 649KB
https://www.youtube.com/watch?v=uojwMhQpjq8
Apr 30, 2012 · Concerta® XL is a convenient once daily formulation using a sophisticated 3-phase delivery system that allows 12 hour symptom control to cover the full active day. The immediate release component ...Author: Rajesh S
https://www.sciencedirect.com/topics/nursing-and-health-professions/osmotic-controlled-release-oral-delivery-system
The simplest oral osmotic system is the single-compartment EOP, which is suitable for active agents that demonstrate an intermediate solubility range. On the other hand, for extremely soluble or insoluble active agents, the push-pull OROS® system (Figure 6.10) is the most useful. In this type of osmotic pump, the water enters the two layers at ...
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