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https://www.sciencedirect.com/science/article/pii/S0168365908004690
5. “Surface-controlled” drug delivery systems. Surface release of drugs from thin, drug-containing films or release of drugs from coated oral tablets were among the earliest surface-controlled DDS, which is another form of controlled drug delivery. These DDS have been clinically successful since the 1960s.Author: Allan S. Hoffman
https://www.ncbi.nlm.nih.gov/pubmed/18817820
Dec 18, 2008 · This paper describes the earliest days when the "controlled drug delivery" (CDD) field began, the pioneers who launched this exciting and important field, and the key people who came after them. It traces the evolution of the field from its origins in the 1960s to (a) the 1970s and 1980s, when ...Author: Allan S. Hoffman
https://www.researchgate.net/publication/23281583_The_origins_and_evolution_of_controlled_drug_delivery_systems
However, a highly detailed review describing the evolution of controlled drug delivery systems from their non-biodegradable macro-scaled state, up to the more updated biocompatible nano-carriers ...Author: Allan Hoffman
https://www.onlinelibrary.wiley.com/doi/10.1002/9781118833322.ch15
Mar 25, 2016 · Unmet clinical needs, establishment of drug biopharmaceutics and pharma‐cokinetics, availability of novel materials, use of biological molecules as therapeutic agents and introduction of new technologies enabled the development of controlled drug delivery systems. This chapter discusses the evolution of controlled release drug delivery ...Author: Krishnaveni Janapareddi, Bhaskara R. Jasti, Xiaoling Li
http://engineering.uci.edu/events/2010/12/origins-and-evolution-controlled-drug-delivery-systems
The earliest controlled drug delivery devices to reach the clinic were macroscopic in size, and were implanted sub-cutaneously, applied topically on the skin or to mucosal regions of the body, or ingested as tablets. These devices were designed to provide “zero order” drug delivery.
https://link.springer.com/chapter/10.1007%2F978-1-4614-1004-1_1
Aug 03, 2011 · A Short History of Controlled Drug Release and an Introduction. ... transit of dosage forms. Much has been achieved but there is still much to learn. This chapter outlines the historical evolution of concepts, practices, and achievements in providing better delivery systems for drugs so that they are better medications. ... The origins and ...Author: Alexander T. Florence
http://www.thepharmajournal.com/vol1Issue10/Issue_dec_2012/3.1.pdf
controlled drug delivery applications.Sixty million patients benefit from advanced drug delivery systems today, receiving safer and more effective doses of the medicines they need to fight a variety of human ailments, including cancer. Controlled Drug Delivery (CDD) occurs when a …
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