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https://pdfs.semanticscholar.org/ec84/3d7dabecf7498324497488d784fe0f845070.pdf
development of oral sustained release drug delivery systems. The goal in designing sustained release drug delivery system is to reduce the frequency of the dosing, reducing the dose & providing uniform drug delivery. So, Sustained release dosage form is a dosage form that releases one or more drugs continuously in predeterminedFile Size: 406KB
https://www.academia.edu/4635543/Sustained_Release_Oral_Drug_Delivery_System_-An_Overview
Developing oral sustained release matrix tablets for drug with constant release rate has always been a challenge to the pharmaceutical technologist. Drug release through matrix system is determined by Water penetration, Polymer swelling, Drug dissolution, Drug diffusion…
https://www.researchgate.net/publication/270275859_Sustained_Release_Drug_Delivery_Systems_A_Patent_Overview
Sustained Release Drug Delivery System (SRDDS) is designed to release a drug at a predetermined rate by maintaining a constant drug level for a specific period of time with minimum side effects. Now a day’s focus on the development of SRDDS has increased,...
https://www.researchgate.net/publication/307671765_ORAL_CONTROLLED_RELEASE_DRUG_DELIVERY_SYSTEM_AN_OVERVIEW
The aim of oral controlled release drug delivery system is to achieve better bioavailability and release the drug from the system to the target site, which should be predictable and reproducible ...
http://globalresearchonline.net/journalcontents/v54-1/02.pdf
systems include any drug-delivery system that achieves slow release of drug over an extended period of time. Sustained Release is also providing promising way to decrease the side effect of the drug by preventing the fluctuation of the therapeutic concentration
http://www.ijpacr.com/files/06-07-15/204072015.pdf
Oral controlled release drug delivery is a system that provides continuous oral delivery of drugs at predictable and reproducible kinetics for a predetermined period throughout the course of GI transit and also the system that target the delivery of a drug to a specific region within the GI tract for either a local or systemic action (Vora et al., 1996). Classification of Oral Controlled Release System
http://ijrpns.com/article/SUSTAINED%20AND%20CONTROLLED%20DRUG%20DELIVERY%20SYSTEM%20-%20AS%20A%20PART%20OF%20MODIFIED%20RELEASE%20DOSAGE%20FORM.pdf
SUSTAINED RELEASE DRUG DELIVERY SYSTEM Sustained release tablet owing a twofold or greater reduction in frequency of administration of a drug in comparison with the frequency required by a conventional dosage form. It is designed to maintain constant levels of a drug …
https://www.researchgate.net/publication/317714183_Modified_Release_drug_delivery_systems
Oral extended release drug delivery system becomes a very promising approach for those drugs that are given orally but having the shorter half-life and high dosing frequency.Author: Shreyas Deo
https://www.researchgate.net/publication/316643864_SUSTAINED_RELEASE_DOSAGE_FORM_A_CONCISE_REVIEW
The design of oral sustained release DDS depends on various factors such as, physicochemical properties of drug, type of delivery system, disease being treated, and patient condition, and treatment duration , presence of food, gastrointestinal motility, and co-administration of other drugs.
https://www.pharmatutor.org/articles/oral-controlled-release-drug-delivery-system-review
Drugs existing largely in ionized form are poor candidate for oral controlled release drug delivery system because absorption rate of ionized drug is 3-4 times less than that of unionized form. The pKa range for acidic drug whose ionization is pH sensitive is around 3.0-7.5 and for basic drug whose ionization is pH sensitive is around 7.0-11.0 are ideal for optimum positive absorption.Author: M Gahlyan, S Jain
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