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https://www.semanticscholar.org/paper/A-Review-on-Oral-Mucosal-Drug-Delivery-System-Hooda-Tripathi/666cff7364f5f84f4850bcd25621089c8080c800
It is the objective of this article to review the oral mucosal drug delivery by discussing briefly the structural feature of mucosa as drug delivery such as buccoadheshive film & tablet, medicated chew gum, fast dissolving tablet, film & capsule etc. Keyword: Buccal Drug Delivery, NDDS, Quick Action, Absorption via buccal mucosa
http://www.thepharmajournal.com/vol1Issue1/Issue_March_2012/3.pdf
The oral mucosal surface is constantly washed by the saliva (daily turn out is about 0.5 to 2 liters). The drug absorption across the oral mucosa occurs in the non-keratinized sections for protein/peptide delivery buccal route offers distinct benefits over other mucosal routes like nasal, vaginal, rectal, etc.
https://www.sciencedirect.com/science/article/abs/pii/S0168365909005422
Oral mucosal drug delivery is an alternative method of systemic drug delivery that offers several advantages over both injectable and enteral methods and also enhances drug bioavailability because the mucosal surfaces are usually rich in blood supply, providing the means for rapid drug transport to the systemic circulation and avoiding, in most cases, degradation by first-pass hepatic metabolism.
http://ijpsr.com/bft-article/a-detailed-review-on-oral-mucosal-drug-delivery-system/?view=fulltext
INTRODUCTION: Oral mucosal drug delivery system is subdivided into buccal and sublingual in which buccal cavity is widely applicable for drug administration through mucosa in case of sublingual route mostly useful for fastest onset of action as in the case of Angina pectoris. The buccal mucosa lines the inner cheek, and buccal formulations are placed in the mouth between the upper gingivae (gums) and …
https://www.pharmatutor.org/articles/oral-mucoadhesive-drug-delivery-systems-review
ADVANTAGES OF ORAL MUCOADHESIVE DRUG DELIVERY SYSTEMS. 1. Prolongs the residence time of the dosage form at the site of absorption, hence. 2. increases the bioavailability. 3. Excellent accessibility, rapid onset of action.
https://www.researchgate.net/publication/266050697_A_detail_review_on_oral_mucosa_of_drug_delivery_system
Oral mucosal drug delivery system is widely applicable as novel site for administration of drug for immediate and controlled release action by preventing first pass metabolism and enzymatic degradation due to GI microbial flora. Oral mucosal drug delivery system provides local and systemic action.
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