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https://fotheme.xyz/drug-delivery-to-the-oral-cavity-pdf/
Drug Delivery to the Oral Cavity PDF Drug Delivery to the Oral Cavity PDF Free Download Drug Delivery to the Oral Cavity PDF Drug Delivery to the Oral Cavity Ebook Content The oral cavity (OC) and its highly permeable mucosal tissues have been taken advantage of for decades as a site of absorption for delivery ...
https://www.ncbi.nlm.nih.gov/pubmed/12126458
Oral mucosal drug delivery is an alternative method of systemic drug delivery that offers several advantages over both injectable and enteral methods. Because the oral mucosa is highly vascularised, drugs that are absorbed through the oral mucosa directly enter the systemic circulation, bypassing the gastrointestinal tract and first-pass metabolism in the liver.Author: Hao Zhang, Jie Zhang, James B. Streisand
https://www.springer.com/gp/book/9781489975577
The book describes the anatomical and physiological challenges of this route for drug delivery and how they impact the design of oral mucosal drug delivery systems. It also provides a detailed description of current oral mucosal drug delivery technologies that overcome these challenges alongside research, development and assessment methods.
https://www.researchgate.net/publication/266050697_A_detail_review_on_oral_mucosa_of_drug_delivery_system
Oral mucosal drug delivery system is widely applicable as novel site for administration of drug for immediate and controlled release action by preventing first pass metabolism and enzymatic degradation due to GI microbial flora. Oral mucosal drug delivery system provides local and systemic action.
https://pdfs.semanticscholar.org/b0a8/905cbaeb0f35d1770ebf43e550130f8bcdf4.pdf
thermore, oral transmucosal drug delivery bypasses first-pass effects in the GI tract and liver and avoids GI side effects. Un-like the nasal cavity, however, drug delivery via the oral cavity is highly acceptable by patients. The mucosa is relatively per-meable, has …
https://www.imedpub.com/articles/a-comprehensive-review-on-buccal-drug-delivery-system.pdf
the oral mucosal cavity, the buccal region offers an adorable route of administration for systemic drug delivery. Among the various transmucosal sites available, mucosa of the buccal cavity was found to be the most convenient and easily approachable site for the delivery of therapeutic agents for both local and systemic delivery as
http://ijpsr.com/bft-article/a-detailed-review-on-oral-mucosal-drug-delivery-system/?view=fulltext
INTRODUCTION: Oral mucosal drug delivery system is subdivided into buccal and sublingual in which buccal cavity is widely applicable for drug administration through mucosa in case of sublingual route mostly useful for fastest onset of action as in the case of Angina pectoris. The buccal mucosa lines the inner cheek, and buccal formulations are placed in the mouth between the upper gingivae (gums) and …
https://www.researchgate.net/publication/8460157_Mucosal_Drug_Delivery_Membranes_Methodologies_and_Applications
Drug delivery via the oral mucosa can be subdivided into three different approaches: sublingual delivery across the mucosa lining the floor of the mouth, buccal delivery via the mucosa lining the ...
https://www.academia.edu/2325046/A_REVIEW_ON_BUCCAL_DRUG_DELIVERY_SYSTEM
A REVIEW ON BUCCAL DRUG DELIVERY SYSTEM
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255397/
Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of absorption. The drugs which have local action or those which have maximum absorption in gastrointestinal tract (GIT) require increased duration of stay in GIT.
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