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https://briefs.techconnect.org/wp-content/volumes/Nanotech2007v2/pdf/243.pdf
transfection efficiency. The YCWP DNA delivery system is effective at transfecting macrophages and dendritic cells in vitro and in vivo and is currently being evaluated for the oral and systemic delivery of genes for vaccines and transient gene therapy of a range of diseases. Keywords: yeast cell wall particles, DNA delivery, layer byAuthor: G Ostroff, E Soto
https://www.ncbi.nlm.nih.gov/pubmed/30090893
Aug 23, 2018 · A multi-functional macrophage and tumor targeting gene delivery system for the regulation of macrophage polarity and reversal of cancer immunoresistance. He XY (1), Liu BY , Xu C , Zhuo RX , Cheng SX .Author: Xiao-Yan He, Bo-Ya Liu, Chang Xu, Ren-Xi Zhuo, Si-Xue Cheng
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879154/
Apr 30, 2009 · To evaluate GeRPs for oral delivery of siRNA-mediated gene silencing in vivo, mice were given Dy547-conjugated scrambled or Map4k4 siRNA (20 µg kg −1) contained within fluorescein–GeRPs (4 × 10 9 fluorescein–GeRPs per kg or about 10 8 GeRPs in 200 µl per mouse) by oral gavage once daily for 8 consecutive days (Fig. 4a).Author: Myriam Aouadi, Gregory J. Tesz, Sarah M. Nicoloro, Mengxi Wang, My Chouinard, Ernesto Soto, Gary R. ...
https://www.sciencedirect.com/science/article/pii/S1742706114000178
To our knowledge, this is the first study to demonstrate a macrophage mannose receptor-specific gene delivery system using SM, thereby highlighting a novel specific non-viral delivery system with potential applications in the engineering of macrophages and other MMR-expressing cells.Author: Gui-Xin Ruan, Yu-Zhe Chen, Xing-Lei Yao, Anariwa Du, Gu-Ping Tang, You-Qing Shen, Yasuhiko Tabata, J...
https://www.nature.com/articles/nature07774?error=cookies_not_supported&code=30ac9682-14b9-43aa-9dda-2bcae2ed54be
Apr 30, 2009 · To evaluate GeRPs for oral delivery of siRNA-mediated gene silencing in vivo, mice were given Dy547-conjugated scrambled or Map4k4 siRNA (20 µg kg-1) contained within fluorescein–GeRPs (4 × 10 ...Author: Myriam Aouadi, Gregory J. Tesz, Sarah M. Nicoloro, Mengxi Wang, My Chouinard, Ernesto Soto, Gary R. ...
https://www.nature.com/articles/3301290
Oct 25, 2000 · Oral administration of S. typhimurium, used as a DNA delivery system, resulted in targeted gene expression within macrophages replenishing their immunological functions.Author: P. Paglia, Nadia Terrazzini, K. Schulze, C.A. Guzman, M.P. Colombo
https://www.researchgate.net/publication/272083578_Macrophage_mediated_biomimetic_delivery_system_for_the_treatment_of_lung_metastasis_of_breast_cancer
Macrophage mediated biomimetic delivery system for the treatment of lung metastasis of breast cancer. The biomimetic delivery system (BDS) based on special type of endogenous cells like macrophages and T cells, has been emerging as a novel strategy for cancer therapy, due to its tumor homing property and biocompatibility.
https://www.sciencedirect.com/science/article/pii/S2352304217300272
Adenovirus-mediated gene delivery in regenerative medicine. The use of adenoviral vectors for genetic engineering has opened new areas of investigation in most areas of medicine. From basic science laboratories to multi-center clinical trials, this promising field has captured the attention of the scientific community.Author: Cody S. Lee, Elliot S. Bishop, Ruyi Zhang, Ruyi Zhang, Xinyi Yu, Xinyi Yu, Evan M. Farina, Shujuan Y...
https://jlb.onlinelibrary.wiley.com/doi/full/10.1189/jlb.72.3.417
Kupffer cells play a significant role in the pathogenesis of many inflammatory liver diseases including early alcohol‐induced liver injury. Therefore, a potential therapeutic strategy would be to modulate the activities of macrophages in the liver via a gene delivery system.Author: B. Burke, S. Sumner, N. Maitland, C. E. Lewis
https://link.springer.com/chapter/10.1007%2F978-1-4614-2305-8_4
Feb 01, 2012 · Monocytes and macrophages originate from the mononuclear phagocyte system and form the basis of immune defense system of the body. These cells are distributed throughout the body, are highly diverse functionally, and work in conjunction …Author: Shardool Jain, Mansoor Amiji
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