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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167783/
Sep 06, 2011 · Oral delivery of antigen by nirB-driven Salmonella typhimurium type III secretion system is a novel, safe, inexpensive, efficient and convenient approach for schistosome vaccine development. Author Summary. Schistosomiasis japonica is a zoonotic parasitic disease and occurs predominantly in Southeast Asia and China. Using a simple, cheap, yet ...Author: Guo Chen, Yang Dai, Jianxiang Chen, Xiaoting Wang, Bo Tang, Yinchang Zhu, Zichun Hua
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582797/
Jun 15, 2013 · Oral boosters of vaccine antigens after priming confer both mucosal and systemic immunity and protection against pathogen or toxin challenge. Oral delivery of autoantigens confers tolerance and relief against allergic immune responses. Oral delivery of biopharmaceutical proteins confer desired functions (e.g. regulation of blood glucose levels).Author: Kwang-Chul Kwon, Dheeraj Verma, Nameirakpam D. Singh, Roland Herzog, Henry Daniell
https://www.sciencedirect.com/science/article/pii/S0141813016305414
ECPs of V. anguillarum were investigated in relation to its virulence and could be regarded as bacterial antigen . At present, oral vaccination was an ideal delivery way in intensive aquaculture for fish farmers, which offered significant advantages over needle-based vaccines, such as easy handling, low cost of production and being stress free ...Author: Ping Gao, Guixue Xia, Zixian Bao, Chao Feng, Xiaojie Cheng, Ming Kong, Ya Liu, Xiguang Chen
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/oral-drug-delivery
Oral Drug Delivery. Oral drug delivery (ODD) is the most preferred and convenient route of drug administration due to high patient compliance, cost-effectiveness, least sterility constraints, flexibility in the design of dosage form and ease of production.
https://link.springer.com/article/10.2165%2F00003088-199732040-00004
Oct 25, 2012 · In most cases the antibodies were administered systemically by the intravenous route. More recently, however, there has been increasing interest in the oral administration of antibodies for localised treatment of infections or other conditions in the gastrointestinal tract.Author: Raymond M. Reilly, Rommel Domingo, Jasbir Sandhu
https://ir.library.oregonstate.edu/downloads/c534fr20v
An oral antigen delivery system was developed for salmonides using fluid-bed spray dry technique. The delivery system was prepared by spraying antigen on to non pareil sugar beads to form an antigen layer, then an enteric protected polymer polymethacrylic acid …
https://iai.asm.org/content/66/9/4299
Sep 01, 1998 · Liposomes appear to be a promising oral antigen delivery system for the development of vaccines against infectious diseases, although their uptake efficiency by Peyer’s patches in the gut and the subsequent induction of mucosal immunoglobulin A (IgA) responses remain a major concern. Aiming at targeted delivery of liposomal immunogens, we have previously reported the conjugation via a ...Author: Evlambia Harokopakis, George Hajishengallis, Suzanne M. Michalek
http://www.pmlive.com/pharma_intelligence/oral_biologics_delivery_still_elusive_908436
Oral biologics delivery still elusive. The search for a better delivery method for peptide, protein and antibody drugs Despite decades of effort, oral delivery of peptide, protein and antibody drugs remains a major pharmaceutical challenge, with only a handful of products on the market.
https://www.medscape.com/viewarticle/581891
Oct 18, 2019 · In this article, we summarize recent progress on oral vaccine delivery and explore the feasibility of such an approach to protect against diseases transmitted through non-mucosal routes.
https://www.cell.com/trends/biotechnology/fulltext/S0167-7799(18)30062-3
Jul 01, 2018 · Antigen-specific immune tolerance (ASI) is a promising approach to treat or prevent autoimmune disorders. Various biomaterials and different routes are being explored for design and effective delivery of antigens to achieve ASI.Author: Akhilesh Kumar Shakya, Kutty Selva Nandakumar, Kutty Selva Nandakumar
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