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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061492/
Topical instillation of ophthalmic drops is the most common method used to administer pharmaceutical agents for ocular disease; 90% of ophthalmic drug formulations are for topical drop use. Methods of topical drug delivery include eye drops, ointments, suspensions, contact lenses, and some drug delivery devices.Author: Henry F. Edelhauser, Cheryl L. Rowe-Rendleman, Michael R. Robinson, Daniel G. Dawson, Gerald J. Chad...
https://www.healio.com/ophthalmology/cornea-external-disease/news/print/ocular-surgery-news/%7Bd69fee03-15c5-4fbd-a090-4f8a5b294c17%7D/understanding-topical-ophthalmic-drug-delivery-how-much-gets-in
Understanding topical ophthalmic drug delivery: How much gets in? Several obstacles stand in the way of effective ocular drug penetration. Ocular Surgery News U.S. Edition, January 10, 2019
https://www.mdpi.com/journal/pharmaceutics/special_issues/ophthalmic_drugdelivery
Drug delivery to the posterior segment of the eye remains a great challenge in the pharmaceutical industry due to the complexity and particularity of the anatomy and physiology of the eye. Some advances have been made with the purpose of maintaining constant drug levels in the site of action.
http://jpet.aspetjournals.org/content/early/2019/05/09/jpet.119.256933
Jan 01, 2019 · An ideal drug delivery system should be designed to enhance drug bioavailability, provide controlled and sustained release of drug at site of action and overcome various ocular barriers. Conventional ophthalmic medications includes the use of topical eye drops and intravitreal injections of anti-VEGF agent for treatment of anterior and posterior segment disorders respectively.Author: Vrinda Gote, Sadia Sikder, Jeff Sicotte, Dhananjay Pal
https://www.sciencedirect.com/science/article/pii/S1350946297000025
Ophthalmic Drug Delivery Systems Topically applied drugs reach the bloodstream mainly via absorption across the mucosa in the nasal cavity which is contiguous with …Author: Chrystèle Le Bourlais, Liliane Acar, Hosein Zia, Pierre A. Sado, Thomas Needham, Roger Leverge
https://www.researchgate.net/profile/Sudip_Das4/publication/279418971_Microparticles_and_Nanoparticles_in_Ocular_Drug_Delivery/links/5b8cd0e3299bf1d5a73a0ba4/Microparticles-and-Nanoparticles-in-Ocular-Drug-Delivery.pdf
ophthalmic drug delivery technique that may enhance dosage form accept- ability while providing sustained release in the ocular milieu (14). Particulate drug delivery consists of systems described ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834898/
Mar 21, 2012 · Glaucoma is a progressive optic neuropathy and medical therapy is the initial option for the treatment of this potentially blinding condition. Topical instillation of eye drops from the bottle is the common ophthalmic drug delivery form. Eye drops usually penetrate via corneal or scleral route, although some conjunctival contribution is noted ...Author: Ingrida Januleviciene, Lina Siaudvytyte, Ruta Barsauskaite
https://www.ondrugdelivery.com/magazines/ophthalmic-drug-delivery104/
optimising ophthalmic drug delivery for therapeutic effectiveness Barbara Morgan discusses how eye physiology impacts product formulation and choice of dosage form, and how advanced delivery technologies are providing new options for formulators seeking to improve the bioavailability or stability of their ophthalmic treatments.
https://www.sciencedirect.com/science/article/pii/S181808761730990X
Due to the unique structure of the eye, which inhibits the entry of drug molecules into the desired site, the ophthalmic delivery of the drug has been one of the most challenging tasks for a pharmaceutical scientist. Eye drops accounts for more than 90% of ophthalmic preparations on the markets.Author: Yumei Wu, Yuanyuan Liu, Xinyue Li, Dereje Kebebe, Dereje Kebebe, Bing Zhang, Jing Ren, Jun Lu, Jiawe...
https://en.wikipedia.org/wiki/Ophthalmic_drug_administration
Ophthalmic drug administration is the administration of a drug through the eyes, most typically as an eye drop formulation. This medical treatment–related article is a stub.
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