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https://ufdc.ufl.edu/UF00091523/00450
Ophthalmic Drug Delivery through Contact Lenses Michael Abrahamson ABSTRACT Current ophthalmic drug delivery systems are insufficient, specifically eye drops, which allow approximately 95% of the drug contained in the drops to be lost due to absorption through the conjunctiva or through the tear drainage.
https://www.ncbi.nlm.nih.gov/pubmed/15223815
Ophthalmic drug delivery through contact lenses. Gulsen D(1), Chauhan A. Author information: (1)University of Florida, Chemical Engineering Department, Gainesville, 32611, USA. PURPOSE: Currently available ophthalmic drug delivery systems are inefficient and may lead to side effects.Author: Derya Gulsen, Anuj Chauhan
https://www.clspectrum.com/issues/2012/november-2012/ophthalmic-drug-delivery-through-contact-lenses
Nov 01, 2012 · Ophthalmic Drug Delivery Through Contact Lenses Contact lenses could alleviate patient noncompliance and offer a more efficient drug delivery system. Anuj Chauhan is a professor and the director of the Graduate Programs in Chemical Engineering at the University of Florida.
https://www.researchgate.net/publication/8484262_Ophthalmic_Drug_Delivery_through_Contact_Lenses
Ophthalmic Drug Delivery through Contact Lenses. ... Contact lenses for ophthalmic drug delivery have become very popular, due to their unique advantages like extended wear and more than 50% ...
https://www.researchgate.net/publication/233873735_Contact_Lenses_Promising_Devices_for_Ocular_Drug_Delivery
Abstract In the ocular pharmacology market, there is a noteworthy unmet demand for more efficacious delivery of ocular therapeutics. Contact lenses are emerging as an alternative ophthalmic drug ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5039753/
Ocular drug delivery to the eyes through contact lenses has received much attention. Assuming the correlation of drug concentration at an intended site of action to pharmacological effects, drug delivery through contact lenses would provide a better control of drug concentration at the eyes 2,3.Author: Dasom Lee, Seungkwon Cho, Hwa Sung Park, Inchan Kwon
https://www.sciencedirect.com/science/article/pii/S0142961208000574
The physical properties of most gels are appropriate for contact lens applications with GEL5 being the most suitable. GEL5 also releases drugs for about 15–20 days and so these materials may be the best candidates for making contact lenses for extended ophthalmic drug delivery.Author: Jinah Kim, Anthony Conway, Anuj Chauhan
https://www.sciencedirect.com/science/article/pii/S1773224714500214
Review of ophthalmic drug delivery by contact lenses K.-H. Hsu, S. Gause, A. Chauhan, â Ž [email protected] Department of Chemical Engineering, 1006 Center Drive, University of Florida, Gainesville, FL 32611, United States Department of Chemical Engineering, 1006 Center Drive University of Florida Gainesville FL 32611 United States * Correspondence Ophthalmic drugs are almost exclusively ...Author: K.-H. Hsu, S. Gause, A. Chauhan
https://www.eyehealthweb.com/drug-dispensing-contact-lenses/
The drug-delivery contact lenses have so far been tested only on an animal model. Before drug-delivering contact lenses can be made available on the market for eye doctors to prescribe, they must first go through rigorous clinical trials and be approved by the US Food and Drug Administration.
https://onlinelibrary.wiley.com/doi/full/10.1111/cxo.12592
Strategies investigated to modify and extend drug release times from existing contact lenses or novel contact lens materials. Drug release can be modified through molecular imprinting, where areas within a polymer are generated at a molecular level to specifically interact non‐covalently to molecules of interest and thus slow diffusion from the material (A), through incorporation of a drug ...Author: Alex Hui
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