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http://intranet.tdmu.edu.ua/data/kafedra/internal/pharma_3/lectures_stud/Industrial%20drugs%20technology/4-course/English/Technology%20of%20eye%20preparations..htm
Drug Delivery: Ophthalmic Route 1221 uco–Oral Ocusert At about the same time as investigations were being carried out with contact lens materials for drug release, an ethylene vinyl acetate (EVA) membrane device, Ocusert_ was developed by the Alza Corp. (Palo …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3061492/
Topical instillation of ophthalmic drops is the most common method used to administer pharmaceutical agents for ocular disease; 90% of ophthalmic drug formulations are for topical drop use. Methods of topical drug delivery include eye drops, ointments, suspensions, contact lenses, and …Author: Henry F. Edelhauser, Cheryl L. Rowe-Rendleman, Michael R. Robinson, Daniel G. Dawson, Gerald J. Chad...
https://www.healio.com/ophthalmology/cornea-external-disease/news/print/ocular-surgery-news/%7Bd69fee03-15c5-4fbd-a090-4f8a5b294c17%7D/understanding-topical-ophthalmic-drug-delivery-how-much-gets-in
Understanding topical ophthalmic drug delivery: How much gets in? Several obstacles stand in the way of effective ocular drug penetration. Ocular Surgery News U.S. Edition, January 10, 2019
https://www.msdvetmanual.com/pharmacology/systemic-pharmacotherapeutics-of-the-eye/routes-of-administration-for-ocular-medications
Routes of Administration for Ocular Medications. The three primary methods of delivery of ocular medications to the eye are topical, local ocular (ie, subconjunctival, intravitreal, retrobulbar, intracameral), and systemic. The most appropriate method of administration depends on the area of the eye to be medicated.
http://samples.jbpub.com/9781284025682/9781449674250_CH10.pdf
Drug delivery to the eye can be generally classified into anterior and posterior segments. Conventional delivery systems, including eye drops, suspensions, and ointments, cannot be considered optimal; however, more than 90% of the marketed ophthalmic formula-
https://www.mdpi.com/1999-4923/12/1/22/pdf
Some rarely used additional routes of local ocular drug delivery (including subretinal and suprachoroidal) are also available (Figure1B). The drug bioavailability depends on the route of drug administration into the eye. Therefore, the anatomical and physiological features of the eye must be taken into account when designing drug delivery systems.Author: Natallia Dubashynskaya, Daria Poshina, Sergei Raik, Arto Urtti, Yury A. Skorik
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
May 01, 2010 · The oral route is not predominant, and only a limited number of compounds were investigated for ocular drug delivery. These include various classes of drugs such as analgesics ( 25 ), antibiotics ( 21 , 26 – 28 ), antivirals ( 29 ), antineoplastic agents ( 30 ), and omega-6 fatty acids …Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra
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