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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044930/
Closed-Loop Delivery. An effective alternative to open loop insulin delivery is closed-loop delivery, in which the involvement of the patient in maintaining glucose control is minimal. Such a system would be able to determine the insulin requirement in real time, regardless of …Author: Terry G. Farmer, Thomas F. Edgar, Nicholas A. Peppas
https://www.sciencedirect.com/science/article/pii/S0378517317311195
Unlike open-loop systems including immediate-release and sustained-release formulations, these smart drug delivery systems release therapeutics with tunable amount at the right time, thus controlling drug release as a function of biosignals relevant to pathological processes (Byrne et al., 2002, Caldorera-Moore et al., 2011) .Author: Jicheng Yu, Yuqi Zhang, Junjie Yan, Anna R. Kahkoska, Zhen Gu
https://www.diabetesnet.com/diabetes-technology/comparison-of-automated-insulin-delivery-systems/
Tidepool’s bet is that the Loop open-source algorithm, currently in use by thousands of people with Type 1 diabetes, might speed FDA approval. However, in May 2019, the FDA issued a warning about DIY Artificial Pancreas Systems (DIY APS) after someone experienced an …
http://web.stanford.edu/group/sohlab/cgi-bin/wordpress/wp-content/uploads/2017/05/News-and-Views-on-Mage-Closed-loop...live-animals.pdf
DRUG DELIVERY Closed-loop dynamic dosing A system consisting of an aptamer-based microfluidic biosensor and a simple feedback-control algorithm adjusts therapeutic dosing in near real time in small animals. Rohit Karnik Infusion pump Real-time biosensor Controller Aptamer e– e– ˜ ˜ ˜˚˛ Figure 1 Closed-loop control of drug infusion ...
https://www.ncbi.nlm.nih.gov/pubmed/18660650
Closed-loop systems for drug delivery. Fields AM(1), Fields KM, Cannon JW. ... PURPOSE OF REVIEW: To discuss closed-loop systems, the engineering behind them, and the application of these systems. RECENT FINDINGS: The literature demonstrates that closed-loop systems can be used for controlling the depth of anesthesia, muscle relaxation, blood ...Author: Aaron M Fields, Kevin M Fields, Jeremy W Cannon
https://www.slideshare.net/chandiniyrao/newer-drug-delivery-systems-85749578
Jan 05, 2018 · Newer drug delivery systems 1. NEWER DRUG DELIVERY SYSTEMS - Dr. Chandini - Moderator: Dr. Princy Pallatty 1 2. Introduction - • Drug delivery systems refers to approaches, formulations, technologies, and systems for transporting a pharmaceutical compound in the body as needed to safely achieve its desired therapeutic effect.
https://www.pnas.org/content/114/48/E10281
Nov 28, 2017 · With control, we were able to deliver a higher DOX dose while maintaining a safe exposure level. This result confirmed the ability of the proposed closed-loop system to tailor the drug delivery dosage within a therapeutically effective range, while improving safety control.Author: Tao Sun, Tao Sun, Yongzhi Zhang, Chanikarn Power, Phillip M. Alexander, Jonathan T. Sutton, Muna Ary...
https://www.slideshare.net/shreeraj9183/intelligent-drug-delivery-system
Sep 21, 2012 · Open-loop control systems In the controlled drug delivery field, open- loop systems are known as pulsed or externally regulated system. The externally controlled devices apply external triggers for pulsed delivery of drug such as: magnetism, ultrasound, and electrical effect etc.It involves following systems : Magnetically modulated drug ...
https://www.sciencedirect.com/science/article/pii/B9780081000922000035
Open-loop systems are known as pulsed or externally regulated, and closed-loop systems as self-regulated. A drug delivery system is developed to enable the introduction of a therapeutic substance into the biological organism and improves its efficacy and safety by controlling the rate, time and place of release of drugs in the body .
https://www.medindia.net/patients/patientinfo/drug-delivery-system.htm
Drug delivery systems, is a technology using various chemicals to bind the target drugs, carry them to target organ, tissue or cell where the drug is released at a pre-determined rate.
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