On The Delivery Of Small Interfering Rnas In Mammalian Cells

We have collected information about On The Delivery Of Small Interfering Rnas In Mammalian Cells for you. Follow the links to find out details on On The Delivery Of Small Interfering Rnas In Mammalian Cells.


On the delivery of small interfering RNAs into mammalian cells

    https://www.tandfonline.com/doi/abs/10.1517/17425247.2.4.639
    Aug 11, 2005 · On the delivery of small interfering RNAs into mammalian cells Mouldy Sioud The Norwegian Radium Hospital, Department of Immunology, Molecular Medicine Group, Montebello, N-0310 Oslo, Norway. [email protected]: Mouldy Sioud

On the delivery of small interfering RNAs into mammalian cells

    https://mdanderson.elsevierpure.com/en/publications/on-the-delivery-of-small-interfering-rnas-into-mammalian-cells
    title = "On the delivery of small interfering RNAs into mammalian cells", abstract = "RNA interference is becoming the technique of choice for analysing gene function and drug target validation. In this process, sequence-specific gene inhibition is initiated by small RNA duplexes, known as small interfering RNAs (siRNAs).Author: Mouldy Sioud

On the delivery of small interfering RNAs into mammalian ...

    https://www.researchgate.net/publication/7471414_On_the_delivery_of_small_interfering_RNAs_into_mammalian_cells
    However, a major obstacle to the use of small interfering RNAs (siRNAs) as therapeutics is their delivery across the plasma membrane of cells in vivo.Author: Mouldy Sioud

Retroviral delivery of small interfering RNA into primary ...

    https://www.pnas.org/content/99/23/14943
    Nov 12, 2002 · Furthermore, 21- to 23-nt dsRNAs, or small interfering RNAs (siRNAs), are capable of inducing RNAi in mammalian cells without initiating the sequence-independent dsRNA response . Consequently, the challenge to mammalian biologists has been to develop systems that deliver siRNAs efficiently into mammalian cells.Author: Gregory M. Barton, Ruslan Medzhitov

Antibody mediated in vivo delivery of small interfering ...

    http://www.nature.com/articles/nbt1101
    May 22, 2005 · Delivery of small interfering RNAs (siRNAs) into cells is a key obstacle to their therapeutic application. We designed a protamine-antibody fusion protein to deliver siRNA to HIV-infected …Author: Erwei Song, Pengcheng Zhu, Sang Kyung Lee, Dipanjan Chowdhury, Steven Kussman, Derek M Dykxhoorn, Yi...

Systemic and Specific Delivery of Small Interfering RNAs ...

    https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(16)31673-2
    RNA interference (RNAi) is a gene silencing process induced by 21–23-nucleotide RNA duplexes called small interfering RNAs (siRNAs) and resulting in sequence-specific messenger RNA degradation post-transcriptionally in the cellular cytoplasmic region.Author: Soo In Kim, Duckhyang Shin, Tae Hyun Choi, Jong Chan Lee, Gi-Jeong Cheon, Ki-Yong Kim, Mahnhoon Park...

Delivery of small-interfering RNA (siRNA) to the brain

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698461/
    RNA interference (RNAi) is caused by small (21 − 23 bases long) single-stranded RNA molecules (small-interfering RNA; siRNA), which trigger silencing of target genes in a sequence-specific manner [1,2]. The siRNA's sequence is ‘anti-sense’ (or complementary) to a specific stretch of the messenger RNA (mRNA) transcribed by the target gene.Author: Saroj P Mathupala

Small-RNA asymmetry is directly driven by mammalian ...

    https://www.nature.com/articles/nsmb.3050
    Jun 22, 2015 · However, the precise mechanisms of small-RNA asymmetry are unclear, especially because asymmetric selection can still occur when the putative asymmetry sensors Drosophila R2D2 and mammalian Dicer ...Author: Hiroshi I Suzuki, Hiroshi I Suzuki, Akihiro Katsura, Takahiko Yasuda, Toshihide Ueno, Hiroyuki Mano,...

Short Hairpin RNA (shRNA): Design, Delivery, and ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679364/
    In recent years, the use of RNA interference (RNAi) has emerged as a powerful tool for the study of gene function in mammalian cells. The mechanism of RNAi is based on the sequence-specific degradation of host mRNA through the cytoplasmic delivery of double-stranded RNA (dsRNA) identical to the target sequence . Degradation of target gene expression is achieved through an enzymatic pathway involving the endogenous RNA-induced …Author: Chris B. Moore, Elizabeth H. Guthrie, Max Tze-Han Huang, Debra J. Taxman

Searching for On The Delivery Of Small Interfering Rnas In Mammalian Cells?

You can just click the links above. The data is collected for you.

Related Delivery Info