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https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/oligonucleotide-delivery
For oligonucleotide delivery experiments, murine bone marrow macrophages are cultured as described above. After 6 days of culture, macrophages are suspended in endotoxin-free PBS at 4° without CaCl 2 and MgCl 2, centrifuged, and washed in DMEM supplemented with 10% FBS (DME-10F).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381599/
Traditionally, systemic delivery of oligonucleotide drugs has been performed by intravenous injection of either naked molecules or within delivery systems, but nonspecific accumulation in various tissues has favored local delivery routes such as to the lungs so as to ensure direct access to the target site.Author: Jørgen Kjems, Kenneth A Howard
https://onlinelibrary.wiley.com/doi/abs/10.1002/anie.201914751
Jan 29, 2020 · Systemic Brain Delivery of Antisense Oligonucleotides across the Blood–Brain Barrier with a Glucose‐Coated Polymeric Nanocarrier. Dr. Hyun Su Min. Department of Materials Engineering, Graduate School of Engineering, The University of Tokyo, …Author: Hyun Su Min, Hyun Jin Kim, Mitsuru Naito, Satomi Ogura, Kazuko Toh, Kotaro Hayashi, Beob Soo Kim, Sh...
http://www.healthtech.com/oligonucleotide/
The Oligonucleotide Therapeutics and Delivery conference, April 4-5, in Cambridge, MA will gather leading drug developers and discovery scientists to discuss technological and scientific advances in oligonucleotide-based therapeutics.
https://www.optcongress.com/oligonucleotide
CHI’s Oligonucleotide Discovery and Delivery conference reveals the latest strategies at the forefront of discovery, chemistry and delivery with in-depth sessions on new chemistries, novel delivery mechanisms and the most important preclinical and clinical advances.
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