Ocular Drug Delivery Systems For The Posterior Segment

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Ocular drug delivery systems: An overview

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289909/
    Anterior segment drug delivery advances are witnessed by modulation of conventional topical solutions with permeation and viscosity enhancers. Also, it includes development of conventional topical formulations such as suspensions, emulsions and ointments. Various nanoformulations have also been introduced for anterior segment ocular drug delivery.Author: Ashaben Patel, Kishore Cholkar, Vibhuti Agrahari, Ashim K Mitra

Ocular Drug Delivery: Targeting the Posterior Segment ...

    https://www.oraclinical.com/resource/ocular-drug-delivery-targeting-the-posterior-segment/
    These same anterior segment delivery systems may also be used intravitreally for treatment of posterior segment conditions, according to the companies. Ocular Therapeutix is also developing a 6-month sustained-release anti-VEGF hydrogel injection for retinal diseases such as age-related macular degeneration, RVO, and DME.

A review on recent drug delivery systems for posterior ...

    https://www.sciencedirect.com/science/article/pii/S0753332218306863
    Major proportion of market of ophthalmic products is occupied by topical formulations which includes eye drops (major), eye ointments, contact lens, cul-de-sac inserts, punctual plugs etc. Being the most convenient and efficacious non-invasive route, it is the most preferred especially for drug delivery to anterior segment.Author: Kritika Nayak, Manju Misra

Ocular Drug Delivery

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
    May 01, 2010 · Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood–retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution), and efflux pumps in conjunction pose a ...Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra

Current and future ophthalmic drug delivery systems: A ...

    https://www.sciencedirect.com/science/article/pii/S1359644607004916
    The important indications for ocular drug delivery systems include macular degeneration, viral infections (like CMV infections), glaucoma, ocular inflammations, dry eye syndrome, and retinal degenerations. There are many important indications for ocular drug delivery systems depending on the site of application and the delivered drug.Author: Eva M. del Amo, Arto Urtti

Ocular Drug Delivery: Targeting the Posterior Segment

    http://retinatoday.com/2016/02/ocular-drug-delivery-targeting-the-posterior-segment
    These same anterior segment delivery systems may also be used intravitreally for treatment of posterior segment conditions, according to the companies. Ocular Therapeutix is also developing a 6-month sustained-release anti-VEGF hydrogel injection for retinal diseases such as age-related macular degeneration, RVO, and DME.

Novel Drug Delivery Systems for Posterior Segment Ocular ...

    https://www.researchgate.net/publication/225859576_Novel_Drug_Delivery_Systems_for_Posterior_Segment_Ocular_Disease
    Delivery of drugs to the eye, particularly for the treatment of posterior segment diseases, is a challenging task that requires drug transport across barriers in the eye, which are present for the ...

ocular drug delivery Systems for the Posterior Segment: a ...

    http://retinatoday.com/pdfs/0512RT_F1_Kuno.pdf
    Editor’s note: To follow is a review of ocular drug delivery systems for the posterior segment currently in development. Because of the sheer volume of technologies, we chose to narrow this review by eliminating discussion of those that have US Food and Drug Administration or European Union approval for at least 1 indication.

OCULAR DRUG DELIVERY TECHNOLOGIES: EXCITING TIMES …

    https://www.ondrugdelivery.com/ocular-drug-delivery-technologies-exciting-times-ahead/
    Yasin MN, Svirskis D, Seyfoddin A, Rupenthal ID, “Implants for drug delivery to the posterior segment of the eye: A focus on stimuli-responsive and tunable release systems”. Journal of Controlled Release, 2014, Vol 196, pp 208-221. O’Rourke M, Hanes J, “Ocular Drug Delivery Via Micro- and Nanoparticles”.

Ocular drug delivery systems: An overview – All About Drugs

    https://www.allfordrugs.com/ocular-drug-delivery-systems-an-overview/
    Various nanoformulations have also been introduced for anterior segment ocular drug delivery. On the other hand, for posterior ocular delivery, research has been immensely focused towards development of drug releasing devices and nanoformulations for treating chronic vitreoretinal diseases.

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