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https://en.wikipedia.org/wiki/Ophthalmic_drug_administration
Ophthalmic drug administration is the administration of a drug to the eyes, most typically as an eye drop formulation. Topical formulations are used to combat a multitude of diseased states of the eye. These states may include bacterial infections, eye injury, glaucoma, and dry eye. However, there are many challenges associated with topical delivery of drugs to the cornea of the eye.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289909/
To overcome the ocular drug delivery barriers and improve ocular bioavailability, various conventional and novel drug delivery systems have been developed such as emulsion, ointments, suspensions, aqueous gels, nanomicelles, nanoparticles, liposomes, dendrimers, implants, contact lenses, nanosuspensions, microneedles, and in situ ...Author: Ashaben Patel, Kishore Cholkar, Vibhuti Agrahari, Ashim K Mitra
https://www.slideshare.net/pharmD_maha/ocular-drug-delivery-system-48322893
May 19, 2015 · The ocular drug delivery system. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. If you continue browsing the site, you agree to the use of cookies on this website.
https://www.ijpbs.com/ijpbsadmin/upload/ijpbs_50c8546501de1.pdf
OCULAR DRUG DELIVERY SYSTEMS: release ocular drug delivery system are: It should not induce a foreign-body sensation or long lasting blurring. It should possess more local activity than systemic-effects. It must deliver the drug to the right place, i.e. in targeting the …
https://www.slideshare.net/vsrujanav/ocular-drug-delivery
Aug 21, 2011 · A Seminar on Ocular Drug Delivery System Presented by : V.Srujana M.Pharm Iyr(IIsem) Dept. Of P’ceutics KLR College. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising.
https://www.wjgnet.com/2220-3192/full/v2/i4/78.htm
Drug delivery through topical or systemic route faces a number of challenges limiting their success. Advancements in drug design, drug formulation and devices have led to successful products. But the scientists have experimented with alternate routes of drug delivery that can overcome barriers presented by the more conventional routes.Author: Deep Kwatra, Ashim K Mitra
https://www.allfordrugs.com/ocular-drug-delivery-systems-an-overview/
The development of an ophthalmic drug delivery system based on cyclodextrins is relatively recent, occurring in the Patel GM, et al.: Advances and challenges in ocular drug delivery system early 1990s. Cyclodextrins were introduced in ocular drug formulations initially with the aim of increasing the solubility of lipophilic drugs in solution.
https://www.pharmatutor.org/articles/review-on-ocular-drug-delivery
Advantages of ocular drug delivery systems 1. Increased accurate dosing. To overcome the side effects of pulsed dosing produced by conventional systems. 2. To provide sustained and controlled drug delivery. 3. To increase the ocular bioavailability of drug by increasing the corneal contact time.
https://www.researchgate.net/publication/225897418_OCULAR_DRUG_DELIVERY_SYSTEM_-_A_REVIEW
A successful design of a drug delivery system, therefore, requires an integrated knowledge of the drug molecule and the constraints offered by the ocular route of administration [3].
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