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https://www.ncbi.nlm.nih.gov/books/NBK534870/
Jan 17, 2021 · Nimodipine should start as early as possible or within 96 hours of the diagnosis of subarachnoid hemorrhage. Nimodipine is usually available as capsules of 30 mg. 1It has to be given at least 1 hour before or 2 hours after meals. The adult recommended dose for adults is 60 mg (two 30-mg capsules) every 4 hours for 21 consecutive days.
https://pubmed.ncbi.nlm.nih.gov/31103551/
Early death (3%) and hypotension (1%) were reasons why patients were not started on nimodipine. Only 36 (33%) patients received nimodipine, 60 mg orally every 4 hours for 21 days. In 26 patients (39%), the dose of nimodipine was reduced because of excessive drops in blood pressure. Transient discontinuation occurred in 2 (2%) patients.Cited by: 4
https://www.pdr.net/drug-summary/Nimodipine-nimodipine-1392
Initially, 1 mg/hour IV for 2 hours. Then 1—3 mg/hour IV for 1—2 weeks. Oral therapy should be continued thereafter for 1—3 weeks. NOTE: The IV formulation is not available in the United States. The contents of nimodipine capsules should NEVER be administered intravenously or by …
https://www.webmd.com/drugs/2/drug-10951/nimodipine-oral/details
Nimodipine is taken as directed by your doctor, usually every 4 hours, 1 hour before or 2 hours after a meal. If you are taking the tablet form of this medication, ...
https://www.sciencedirect.com/topics/medicine-and-dentistry/nimodipine
The usual dose of nimodipine is 60 mg by mouth every 4 hours. In those who are particularly susceptible to hypotension, an alternative regimen of 30 mg by mouth every 2 hours can be used. Some of the key studies leading to this management recommendation are summarized briefly.
https://www.drugs.com/dosage/nimodipine.html
Apr 29, 2020 · 60 mg orally, nasogastric, or gastric tube every 4 hours. -Duration of therapy: 21 days. Comments: -Treatment should begin within 96 hours of the onset of subarachnoid hemorrhage (SAH). -IV and other parenteral routes should be avoided. Use: Improvement of neurological outcome by reducing the incidence and severity of ischemic deficits in ...
https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/018869s014lbl.pdf
U.S. 20-30 mg I-III Nimodipine Placebo 56 60 13 16 1 8** French 60 mg I-III Nimodipine Placebo 31 39 4 11 2 10** * Hunt and Hess Grade ** p=0.03 A third, large, study was performed in the United Kingdom in SAH patients with a ll grades of severity (but 89% were in Grades I–III). Nimodipine was dosed 60mg every 4 hours. Outcomes were notFile Size: 146KB
https://www.rxlist.com/nymalize-drug.htm
Feb 10, 2021 · Nimodipine 20-30 mg every 4 hours: 56: 13: 1: Placebo: 60: 16: 8** Study 2: I-III: Nimodipine 60 mg every 4 hours: 31: 4: 2: Placebo: 39: 11: 10** *Hunt and Hess Grade **p=0.03: Study 3 was a 554-patient trial that included SAH patients with all grades of severity (89% were in Hunt and Hess Grades I-III). In Study 3, patients were treated with ...
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