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http://www.nichenet.com/store.htm
NicheNET Inc 18 Minnesota Ave Warwick, RI 02888 401-732-1879 800-856-0595 F: 401-633-6528 [email protected] "In six months time, NicheNET has turned our little online store into a quarter million dollar massive webstore. They don't rely on the tricks, but proven methods to ensure success"
https://github.com/saeyslab/nichenetr
NicheNet uses human or mouse gene expression data of interacting cells as input and combines this with a prior model that integrates existing knowledge on ligand-to-target signaling paths. This allows to predict ligand-receptor interactions that might drive gene expression changes in cells of interest. We describe the NicheNet algorithm in the ...
https://pubmed.ncbi.nlm.nih.gov/31819264/
We applied NicheNet to tumor and immune cell microenvironment data and demonstrate that NicheNet can infer active ligands and their gene regulatory effects on interacting cells. Publication types Research Support, Non-U.S. Gov't MeSH terms Animals Cell Communication* ...
https://saezlab.github.io/OmnipathR/articles/nichenet.html
NicheNet is a method to infer ligand activities from transcriptomics data. It relies on prior knowledge which includes signaling networks and transcriptomics data from ligand perturbation experiments. OmnipathR provides a close integration with NicheNet: it provides methods to build the networks directly from the original sources in a format ...
https://cloud.tencent.com/developer/article/1819551
NicheNet简介 分析原理. 大多数细胞通讯的分析方法主要依据公共数据库的配体-受体配对关系，以及配体、受体在细胞亚群的表达情况来推断细胞之间发生了哪些通讯关系，但是配体-受体相互作用如何导致受体细胞内下游靶基因表达变化的分析则很少有方法涉及。 ...
https://www.nature.com/articles/s41592-019-0667-5
NicheNet uses expression data, in combination with a previous model built on known signaling and gene regulatory networks, to predict ligand–target links in cell-to-cell communications.
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