Noninvasive Delivery

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Noninvasive, Targeted, and Non-Viral Ultrasound-Mediated ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726227/
    A novel approach for noninvasive and targeted GDNFp gene therapy is critically needed. Focused ultrasound (FUS) sonication in conjunction with microbubbles (MBs) has been shown to transiently disrupt the blood-brain barrier (BBB) for noninvasive and targeted delivery of therapeutic substances 16.Author: Ching-Hsiang Fan, Chien-Yu Ting, Chung‐Yin Lin, Hong-Lin Chan, Yuan-Chih Chang, You-Yin Chen, Hao-Li...

Nitric Oxide Delivery by Neonatal Noninvasive Respiratory ...

    http://rc.rcjournal.com/content/60/2/219
    Feb 01, 2015 · RESULTS: Accuracy of NO delivery was determined to be within the stated accuracy by the manufacturer with nasal CPAP and NIV, but accuracy was compromised during HFNC. INO and NO 2 measured by the INOmax DS IR (Ikaria, Hampton, New Jersey) did not consistently reflect the delivered dose of NO or formation of NO 2 across all types of neonatal noninvasive respiratory support.Author: Robert M DiBlasi, Donna Dupras, Christine Kearney, Eddie Costa, Jeffrey L Griebel

Noninvasive delivery of stealth, brain-penetrating ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125545/
    Sep 10, 2014 · Noninvasive delivery of stealth, brain-penetrating nanoparticles across the blood-brain barrier using MRI-guided focused ultrasound. ... Delivery of BPNs with MR-guided FUS has the potential to improve efficacy of treatments for many CNS diseases, while reducing systemic side effects by providing sustained, well-dispersed drug delivery into ...Author: Elizabeth Nance, Elizabeth Nance, Kelsie Timbie, G. Wilson Miller, Ji Song, Cameron Louttit, Alexand...

Non-invasive delivery strategies for biologics Nature ...

    https://www.nature.com/articles/nrd.2018.183
    Nov 30, 2018 · The requirement for delivery by injection is currently a limitation for the use of biologic drugs such as antibodies. In this Review, Mitragotri and colleagues discuss advances made in non ...Author: Aaron C. Anselmo, Yatin Gokarn, Samir Mitragotri

Noninvasive Ventilation: Overview, Methods of Delivery ...

    https://emedicine.medscape.com/article/304235-overview
    Apr 07, 2020 · Noninvasive ventilation has been used as a replacement for invasive ventilation, and its flexibility also allows it to be a valuable complement in patient management. Its use in acute respiratory failure is well accepted and widespread. It is the focus of this review.

Noninvasive Ventilation - an overview ScienceDirect Topics

    https://www.sciencedirect.com/topics/medicine-and-dentistry/noninvasive-ventilation
    Noninvasive Ventilation. Noninvasive ventilation (NIV) is the mainstay of therapy for patients with acute exacerbation of COPD; however, NIV failure is associated with higher risk of hospital mortality.

Comparison of Interfaces for the Delivery of Noninvasive ...

    http://rc.rcjournal.com/content/63/10/1197
    Oct 01, 2018 · BACKGROUND: Bench and clinical data indicate that techniques for applying noninvasive respiratory support may vary in terms of effectiveness, application, and tolerability. We implemented a new nasal interface and flow-generation system for the delivery of noninvasive respiratory support (NRS) to replace previously used systems.Author: Gail S Drescher, Cathy W Hughes

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