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https://www.intechopen.com/books/gene-therapy-tools-and-potential-applications/non-viral-delivery-systems-in-gene-therapy
The successful delivery of therapeutic genes to the desired target cells and their availability at the intracellular site of action are crucial requirements for efficient gene therapy. The design of safe and efficient non-viral vectors depends mainly on our understanding of the mechanisms involved in the cellular uptake and intracellular ...Author: Alicia Rodríguez Gascón, Ana del Pozo-Rodríguez, María Ángeles Solinís
https://www.sciencedirect.com/science/article/pii/S0168365915302649
An overview of non-viral gene delivery tools for non-systemic administration. A) Nucleic acids (DNA, therapeutic oligonucleotides and gene editing) and bio- and nanotechnology tools, including ex vivo methods, used in non-viral gene therapy. B) Schematic diagram of the building blocks, delivery systems and non-invasive administration routes in ...Author: Marianna Foldvari, Ding Wen Chen, Nafiseh Nafissi, Daniella Calderon, Lokesh Narsineni, Amirreza Raf...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2907101/
Gene therapy is defined as the treatment of disease by transfer of genetic material into cells. This review will explore methods available for gene transfer as well as current and potential applications for craniofacial regeneration, with emphasis on future development and design.Author: Erica Scheller, P. H. Krebsbach
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347098/
Jan 01, 2015 · The major advantage of using non-viral vectors is its bio-safety. However the application of non-viral gene transfer have been ignored for a long time in past because of their poor efficiency of delivery thereby low transient expression of their transgenes . Non-viral vectors have drawn significant attention due to its less immunotoxicity.Author: Murali Ramamoorth, Aparna Narvekar
https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-018-1402-1
Feb 15, 2018 · Critical tissue defects frequently result from trauma, burns, chronic wounds and/or surgery. The ideal treatment for such tissue loss is autografting, but donor sites are often limited. Tissue engineering (TE) is an inspiring alternative for tissue repair and regeneration (TRR). One of the current state-of-the-art methods for TRR is gene therapy. Non-viral gene delivery systems (nVGDS) have ...Author: Pan Wu, Haojiao Chen, Ronghua Jin, Tingting Weng, Jon Kee Ho, Chuangang You, Liping Zhang, Xingang W...
https://www.springer.com/gp/book/9784431251224
Non-viral Gene Therapy Gene Design and Delivery. Editors: Taira, Kazunari, Kataoka, Kazunori, Niidome, Takuro (Eds.) Free Preview
https://www.genetherapynet.com/non-viral-vectors.html
Non-viral methods present certain advantages over viral methods, with simple large scale production and low host immunogenicity being just two. Previously, low levels of transfection and expression of the gene held non-viral methods at a disadvantage; however, recent advances in vector technolog...
https://www.amazon.com/Non-viral-Gene-Therapy-Design-Delivery/dp/4431251227
Sep 26, 2005 · Buy Non-viral Gene Therapy: Gene Design and Delivery on Amazon.com FREE SHIPPING on qualified ordersAuthor: AsianTreasures
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