New Methods Of Drug Delivery Through The Blood Brain Barrier

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New approaches to drug delivery through the blood-brain ...

    https://www.sciencedirect.com/science/article/pii/0167779994901236
    The development of recombinant proteins, monoclonal antibodies, or antisense oligonucleotides as pharmaceuticals for the brain will require the parallel development of practical strategies for delivery of these pharmaceuticals in vivo through the endothelial wall of capillaries in the brain, the blood-brain barrier. The brain and spinal cord constitute the only organ to be perfused by ...Author: William M. Pardridge

Modern methods for delivery of drugs across the blood ...

    https://www.sciencedirect.com/science/article/pii/S0169409X11002900
    Modern methods of transporting drugs across the blood–brain barrier As previously stated, the various transport mechanisms across the BBB can be summarised as per Fig. 2 . The paracellular pathway, transcellular pathway, transport proteins, efflux pumps, RMT and adsorptive transcytosis described in Fig. 2 have long been accepted as potential transport routes for drug entering the brain [20] .Author: Yan Chen, Lihong Liu

blood-brain-barrier: New virus-inspired method to deliver ...

    https://health.economictimes.indiatimes.com/news/diagnostics/new-virus-inspired-method-to-deliver-drugs-to-brain-developed-study/71552372
    Oct 12, 2019 · The study, published in the journal Nature Communications, noted that the new method allowed for combination drug delivery through an intravenous injection to cross the blood-brain-barrier …

Better drug delivery through the blood-brain barrier ...

    https://www.drugtargetreview.com/news/36234/deliver-blood-brain/
    Oct 19, 2018 · Drug delivery through the blood-brain barrier has shown to be difficult to overcome, but researchers may have discovered a method to overcome this issue… Research on the delivery of therapeutics to the brain could have implications for the treatment of a wide range of diseases, such as Alzheimer’s, ALS, brain cancer and Parkinson’s.

A Virus-inspired Method for Drug Delivery to the Brain ...

    https://www.news18.com/news/lifestyle/a-virus-inspired-method-for-drug-delivery-to-the-brain-developed-says-study-2343131.html
    Oct 12, 2019 · The study, published in the journal Nature Communications, noted that the new method allowed for combination drug delivery through an intravenous injection to cross the blood-brain-barrier (BBB). The researchers, including those from Newcastle University in the UK, synthesized and modified components from a virus that targets the brain -- a bacteriophage fd -- to deliver drugs across the …

How to Overcome the Blood-Brain Barrier to Deliver New ...

    https://stories.abbvie.com/stories/how-to-overcome-blood-brain-barrier-to-deliver-new-medicines.htm
    Jul 18, 2016 · The blood-brain barrier (BBB) is a complex and intricate system of cells that come together around the blood vessels in the brain. It maintains proper function of the brain, but it also makes it harder to discover and develop new medicines to treat diseases of the brain, such as Alzheimer’s disease, Parkinson’s and others.

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